Robot-assisted training is a promising technology in clinical rehabilitation providing effective treatment to the patients with motor disability. In this paper, a multi-modal control strategy for a therapeutic upper limb exoskeleton is proposed to assist the disabled persons perform patient-passive training and patient-cooperative training. A comprehensive overview of the exoskeleton with seven actuated degrees of freedom is introduced. The dynamic modeling and parameters identification strategies of the human-robot interaction system are analyzed. Moreover, an adaptive sliding mode controller with disturbance observer (ASMCDO) is developed to ensure the position control accuracy in patient-passive training. A cascade-proportional-integral-derivative (CPID)-based impedance controller with graphical game-like interface is designed to improve interaction compliance and motivate the active participation of patients in patient-cooperative training. Three typical experiments are conducted to verify the feasibility of the proposed control strategy, including the trajectory tracking experiments, the trajectory tracking experiments with impedance adjustment, and the intention-based training experiments. The experimental results suggest that the tracking error of ASMCDO controller is smaller than that of terminal sliding mode controller. By optimally changing the impedance parameters of CPID-based impedance controller, the training intensity can be adjusted to meet the requirement of different patients.
Over the past decade, the increasing stroke patient population has brought great economic and medical pressures to the whole society. Surviving stroke patients usually have a lower quality of life dues to physical disability and cognitive impairment. Studies on clinical stroke treatment indicate that appropriate rehabilitation training has positive therapeutic effects for avoiding muscle atrophy and recovering musculoskeletal motor functions. However, the conventional one-on-one manual-assisted movement training conducted by physiotherapists suffers from many inherent limitations, such as high labor intensity, high cost, long time consumption, lack of repeatability, low participation levels of patient, and high dependence on personnel with specialized skills [1,2]. In recent years, robot-assisted rehabilitation therapies have gained growing interest from academic researchers and the healthcare industry around the world due to their unique advantages and promising application perspectives. Compared with the traditional manual rehabilitation treatment, the combination of robotic technologies and clinical experience can significantly improve the performance and quality of training. Robot-assisted therapy is capable of delivering high-intensity, long-endurance, goal-directed, and low-cost rehabilitation treatment. Moreover, the functional motivations of patient can be activated to enhance active participation and recover cognitive functions. The physical parameters and therapy data can be recorded and analyzed via sensing system, and that can provide objective basis to optimize training strategy and accelerate recovery process [3,4].
Many therapeutic robot system have been developed to assist stroke patients with motor dysfunctions perform the desired rehabilitation training. The existing rehabilitation robotic devices can be categorized into two types, i.e., end-effector-based robots and exoskeleton-based robots. End-effector-based robot has only a connection between its distal end and the impaired extremity of patient. However, the movement of end-effector cannot uniquely identify the configuration of human limb due to the kinematic redundancy. Miller et al. developed a lightweight and potable end-effector-based therapeutic robot, which is integrated with a wrist and finger force sensor module named WFES, for the upper limb rehabilitation training of hemiplegic stroke patients . Pedro et al. developed a parallel kinematic mechanism (PKM) with two translational and two rotational degrees of freedom (DOFs) for knee diagnosis and rehabilitation tasks . Kang et al. proposed a modular and reconfigurable wrist robot called CR2-Haptic for post-stroke subjects to train forearm and wrist movements . Besides, many other end-effector-based therapeutic robot have been investigated and can be referred to [8,9,10,11,12,13]. Comparatively, the exoskeleton-based rehabilitation robots are developed with more complex structures imitating the anatomical human skeleton and guaranteeing the alignment between the joints axis of robot and impaired limb. ChARMin is a powered exoskeleton integrated with audiovisual game-like interface. It can provide intensive pediatric arm rehabilitation training for the children and adolescents with affected motor functions . Simon et al. proposed a spherical shoulder exoskeleton with a double parallelogram linkage to eliminate singularities and achieve good manipulability properties . Crea et al. developed a semi-autonomous whole-arm exoskeleton for the stroke patients performing activities of daily living (ADL) utilizing hybrid electroencephalography and electrooculography feedback signals . Many other representative exoskeleton-based therapeutic robot have also been designed, such as CAREX-7 , RUPERT , ULEL , ArmeoPower , Indego , and ETS-MARSE .
The effectiveness of robot-assisted rehabilitation training depends on the control strategies applied in the therapeutic robot system. Currently, many kinds of control strategies have been developed according to the requirements of patients with various impairment severities in different therapy periods. The existing control schemes can be basically divided into two categories based on the interaction between therapeutic robots and patients, i.e., patient-passive training control and patient-cooperative training control. During the acute period of hemiplegia, the impaired extremity is fully paralyzed without any muscle contraction. The patient-passive training can imitate the manual therapeutic actions of a physiotherapist. It is especially well suited for the patients with severe paralysis to passively execute repetitive reaching missions along predefined training trajectories. However, it is a challenge to guarantee the position control accuracy during rehabilitation training due to the highly nonlinear properties and unexpected uncertainties of human-robot interaction. Different kinds of control algorithms have been developed to improve control performance of patient-passive training, including neural proportional-integral-derivative (PID) control , neural proportional-integral (PI) control , adaptive nonsingular terminal sliding mode control (SMC) , disturbance observer-based fuzzy control , neural-fuzzy adaptive control , adaptive backlash compensation control , and so on. Comparatively, the patient-cooperation training is applicable for the patients at the comparative recovery period, who have regained parts of motor functions. Clinical studies show that integrating the voluntary efforts of patients into rehabilitation training benefits to accelerate recovery progress and promote psychological confidence. Thus, patient-cooperation training should be able to regulate the human-robot interaction in accordance with the motion intentions and hemiplegia degrees of patients. Many patient-cooperation control strategies have been proposed, such as minimal assist-as-needed controller , myoelectric pattern recognition controller , electromyography (EMG)-based model predictive controllers , subject-adaptive controller , and fuzzy adaptive admittance controller .
Taking the above into consideration, the contribution of this paper is to develop an upper limb exoskeleton to assist the patient with motor disabilities perform multi-modal rehabilitation training. Firstly, the overall mechanical structure and the MATLAB/xPC-based real-time control system of the proposed therapeutic robot are introduced. Secondly, the dynamic modeling of the human-robot system is researched, and the dynamics parameters are obtained via virtual prototype and calibration experiments. After that, a multi-modal control strategy integrated with an adaptive sliding mode controller and a cascade-proportional-integral-derivative (CPID)-based impedance controller is proposed. The controller is combined with an audiovisual therapy interface and is able to realize patient-passive and patient-cooperation training based on the motor ability of patient. Finally, the effectiveness and feasibility of the developed rehabilitation exoskeleton system and control scheme are verified through three experiments conducted by several volunteers.[…]