Archive for category Books

[BOOK] New Vibratory Device for Wrist Rehabilitation – Innovation, Engineering and Entrepreneurship – Google Books

New Vibratory Device for Wrist Rehabilitation

H Puga – Innovation, Engineering and Entrepreneurship, 2018
Wrist injuries are very common in most of the population, specially bone fractures,
but also other pathologies such as tendinitis and neurological diseases. When the
wrist is injured, their flexion-extension and radial-ulnar deviation and pronation …


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[BOOK] Common Epilepsy Pitfalls: Case-Based Learning – Chapter 3, Radiographic Errors in Epilepsy – Google Books

Cambridge University Press7 Ιουν 2018 – 224 σελίδες
Epilepsy is amongst the most frequently encountered of neurological disorders, yet its diagnosis and management is fraught with pitfalls. Issues surrounding differential diagnosis, seizure type, underlying causes, EEG interpretations, treatment options and prognoses can often trip-up clinicians. Common Epilepsy Pitfalls: Case-Based Learning, is a comprehensive guide to anticipating and managing the pitfalls in the diagnosis and management of epilepsy. Real-life cases are presented along with pragmatic recommendations for courses of action that guide the reader through accurate and effective epilepsy diagnosis and treatment. Cases have been chosen to answer key questions such as: the first seizure – is it epilepsy? Which drug? When should stopping treatment be considered? What to do in an epileptic emergency? Containing detailed coverage of psychiatric, social and family issues – and authored by world experts in epilepsy management – this text is invaluable for neurologists, internists, family practitioners and advanced medical students.

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[BOOK] Rehabilitation Robotics: Technology and Applications – Rehabilitation Robotics

Cover image The last decades have seen major advances in interventions for neuromotor rehabilitation. Forms of treatment based on repetitive exercise of coordinated motor activities have been proved effective in improving gait and arm functions and ultimately the patients’ quality of life. Exercise-based treatments constitute a significant burden for therapists and are heavy consumers of health-care resources. Technologies such as robotics and virtual reality can make them more affordable.

Rehabilitation robotics specifically focuses on systems—devices, exercise scenarios, and control strategies—aimed at facilitating the recovery of impaired sensory, motor, and cognitive skills. The field has a relatively long history, dating back to the early 1990s. Early attempts were part of the general trend toward automating heavy tasks by using “intelligent” machines, with minimal human intervention. The notion of “artificial therapist” was common in early scientific papers and patent applications. However, the most distinctive feature of these devices is not their ability to “automate” treatment but, rather, that of precisely quantifying sensorimotor performance during exercise, in terms of movement kinematics and exchanged forces. This resulted in a gradual shift toward more evidence-based and data-driven forms of treatment. Present-generation rehabilitation robots are designed as complements, rather than substitutes, of the therapist’s work. They support the recovery of functions by efficiently exploiting structure and adaptive properties of the human sensorimotor systems and provide rich information on sensorimotor performance and their evolution. Their design, implementation, and modalities of intervention incorporate findings from behavioral studies on sensorimotor adaptation and motor skill learning and their neural substrates.

Rehabilitation robotics is therefore characterized by highly specific design approaches and technical solutions, with roots in both engineering and neurophysiology.

This book addresses both technology and application aspects of Rehabilitation Robotics. Part I focuses on the state of the art and representative advancements in the design, control, analysis, and implementation of rehabilitation robots and the underlying neurophysiological principles. Part II addresses the existing applications and the clinical validation of these systems, with a special emphasis on therapy robots, which support exercise-based treatments aimed at recovering sensorimotor or cognitive functions.

PART I: Background and Technology


Planning and execution of movements results from the coordinated activity of multiple interconnected sensory and motor areas in the cerebral cortex. When an area in this specialized motor network is damaged—for example, through a traumatic brain injury or an ischemic event—the activity of the motor networks can be disrupted, thus leading to functional deficits. How the surviving motor networks reorganize to compensate for the injury depends on the location and extent of the lesion but may be affected by sensorimotor exercise.

Chapter 1 summarizes how neuroplasticity modifies motor networks in response to injury, by focusing on the changes after a cerebrovascular accident in the primary motor cortex. Neuroanatomical and neurophysiological evidence in animal models and human stroke survivors is reviewed to demonstrate how injuries functionally impair motor networks, how motor networks compensate for the lesion to improve motor function, and how selected therapies may facilitate recovery.

Chapter 2 focuses on the hierarchical architecture and synergistic functioning of the motor system. These aspects are crucial for the development of successful robotics applications with rehabilitation purposes. The same framework is used to discuss the mechanisms underlying rehabilitation interventions with a potential to facilitate the recovery process.

Technology and Design Concepts

Devices for rehabilitation benefit from advances in robot technologies, including sensors and actuators, mechanical architectures, and the corresponding control architectures. These devices are characterized by a continuous interaction with the human body, which poses specific design constraints.

Chapter 3 summarizes the notion of “biomechatronic” design for systems for robot-mediated rehabilitation, encompassing robot structure, musculoskeletal biomechanics, and neural control. Robots for rehabilitation are typically conceived to constantly work in constrained motion with the human body, which represents a challenge for designers. This requires a top-down design approach, in which a model of the human agent guides a concurrent, iterative design cycle of the robot’s mechanical, electronic, and multilayered control subsystems. Criteria for the identification of functional and technical specifications and the selection of key components of the robotic system are also derived. Two design case studies demonstrate how these design principles are translated into practice.

Chapter 4 addresses how actuators play a critical role in defining the characteristics of the robot-patient interaction. The different options for actuating and controlling a rehabilitation device are discussed, considering the complex flow of information between the user and the robot during a rehabilitation task. Strategies for both high- and low-level control are presented. Impedance and admittance control modalities are discussed as means of decoding human intention and/or modulating the assistive forces delivered by the robot. Mathematical tools for model-based compensation of nonlinear phenomena (backlash and friction) are also presented.

The way robots are used to facilitate training is crucial for their application to therapy and has important implications for their mechanical and control design. Intensity and frequency of practice are major determinants of the recovery process, but different exercise modalities are possible. Robots may be used for haptic rendering in virtual environments, to provide forces that facilitate task performance or task completion, and/or to make a task more difficult and challenging.

Chapter 5 reviews the control strategies for robotic therapy devices and summarizes the techniques for implementing assistive strategies, including counterbalance techniques and adaptive controllers that modify control parameters based on the patient’s ongoing performance.

Personalized treatment is becoming increasingly popular in neurorehabilitation. Two chapters discuss how new design techniques such as exoskeletons or wearable robots are applied to the design of modern therapy robots, for either upper or lower limb rehabilitation.

Chapter 6 specifically addresses the design of exoskeletons for upper-limb rehabilitation. After an introduction of the rationale behind the selection of this robot architecture and a review of the available solutions for actuation, the chapter discusses the state of the art and the most commonly adopted solutions. An overview of clinical evidences of upper-limb rehabilitation with exoskeletons is then provided, discussing evidences in favor of training with exoskeleton devices.

Chapter 7 reviews the current state and clinical effectiveness, safety, and usability of exoskeletons for gait rehabilitation. It provides an overview of the actuation technologies, including compliant and lightweight solutions. Control strategies aimed at guiding the patient according to his/her needs and encouraging his/her active participation are also discussed. Novel perspectives for “symbiotic” human-exoskeleton interaction based on interfaces with neural structures are also introduced.

Computational Neurorehabilitation

One important feature of therapy robots is that they integrate both therapeutic and measuring functionalities. Therapy robots have built-in technology and sensors that measure movement kinematics and kinetics, thus providing an accurate assessment of motor function by which it is possible to diagnose the patient state and to evaluate patient performance and their progress during treatment. The availability of quantitative information has triggered an entirely new paradigm for neurorehabilitation, unifying clinical assessment, and exercise. Computational neurorehabilitation is a new and emerging field, which uses modern data analysis and modeling techniques to understand the mechanisms of neural plasticity and motor learning, and incorporates this knowledge into personalized, data- and model-driven forms of treatment.

Chapter 8 reviews the quantitative measures—encompassing kinematic, kinetic, timing, sensory, and neuromechanical aspects of performance—which are most frequently used to describe motor behavior during robot-assisted rehabilitation of the upper limb. The chapter also analyzes how these indicators are used to monitor motor recovery during exercise, to understand the evolution of performance, and to precisely plan and, if necessary, modify the rehabilitation strategies. The relationship between robot-derived measures and their clinical counterparts is also discussed.

Chapter 9 addresses computational models for neuromotor recovery, with a focus on state-space models that describe the development of functional behaviors through exercise and the relation between neuromotor recovery and motor learning. The chapter first reviews models of the dynamics of sensorimotor adaptation and motor skill learning and then elaborates on similarities and differences with neuromotor recovery. Finally, it discusses how these models can be used to achieve a better understanding of the role of robots to promote recovery and to develop personalized forms of treatment.

Chapter 10 proposes a general framework to model the interaction between robot and patient during robot-assisted training. Human and robot are modeled as two agents, whose respective tasks are described by two cost functions. Optimal interaction strategies are then derived in terms of differential game theory. This approach allows to describe different forms of human-robot interaction. A specific prediction is that optimal interaction requires that the robot maintains a model of the behavior of its human partner. In this case, simulations and empirical studies exhibit more stable, reactive, and adaptive interaction. This form of “symbiotic” interaction is a step toward defining what it takes for robots to behave as “optimal” trainers.

Chapter 11 addresses the strategies implemented in rehabilitation robots to promote patient motivation, which is a major determinant of recovery through exercise. Motivation may be measured with self-report questionnaires or with indirect, more objective measures, such as exercise duration. Motivation may be promoted through interaction with virtual environments, which may consist of activities of daily living, which emphasize relatability, or games, which emphasize enjoyment. The design of these environments must take the hardware, the patients’ characteristics, and goal-related feedback into account. Motivation during exercise must be maintained by regulating task difficulty, thus ensuring an appropriate “challenge level.”

Software Environments for Rehabilitation Robotics

As a natural conclusion of this methodological section,  Chapter 12 reviews the software development environments that can be used to implement the different levels of control of a modern rehabilitation robot. The robotic field suffers from a lack of standardization in programming environments. Hence, it is not surprising that even in the specific context of rehabilitation robotics, there is currently no consensus on specific software and hardware platforms. The chapter surveys different solutions used for combining robots (and, more in general, haptic interfaces) and virtual environments. Advantages and disadvantages of each of these environments are discussed, together with typical applications, with a focus on upper-limb rehabilitation.

PART II: Applications

The second part of the book addresses the application of rehabilitation robots in different pathologies for training of diverse districts (upper and lower limb) and using different training strategies.

High Intensity, Assist-As-Needed Therapy to Improve Motor Functions

Chapter 13 provides an overview of 28 + years of efforts at MIT’s Newman Laboratory for Biomechanics and Human Rehabilitation for the developments of robotic tools to assist in the neurorecovery process. After a definition of the basic principles that are core for successful rehabilitation robotics technology, the chapter presents a snapshot of few of MIT’s rehabilitation robots, discusses the results of metaanalyses for upper extremity robotics, and finally presents two exciting examples for acute and chronic stroke. Overall, the above material points out that robotic therapy for the upper extremity that involves an interactive high-intensity, intention-driven therapy based on motor learning principles and assist-as-needed leads to better outcomes than usual care in both acute/subacute and chronic stroke.

The above principles have been extended to training in a three-dimensional workspace, using robots with an exoskeleton structure.  Chapter 14 describes the application of one of the first architectures developed with the purpose of mirroring the anatomical structure of the human arm and of enabling task-oriented training in the 3D space, mimicking activities of daily living.

Hand and finger functions are of critical importance for independence in everyday activities, but their recovery is often limited following neurological injury. This has motivated the development of novel therapeutic and assistive tools.  Chapter 15 provides a comprehensive overview of robotic approaches for the rehabilitation of hand function and underlines their potential to complement conventional rehabilitation. First, the design concepts of existing hand exoskeletons and end-effector devices are presented. Then, clinical evidence that underlines the feasibility of robot-assisted rehabilitation of hand function is presented. Finally, promising research directions are discussed to further exploit the potential of robot-assisted rehabilitation of hand function in neurological patients.

Robot-assisted gait training typically involves body-weight support and physical guidance to move the legs into the correct pattern. Gait rehabilitation robots allow greater exercise duration and movement repetitions; improve patient safety and motivation; reduce the therapists’ burden; and, eventually, improve the therapeutic outcome.  Chapter 16 introduces the rationale for robot-assisted gait training. In particular, existing gait-rehabilitation robots and their control strategies are presented. The available clinical trials are also summarized, showing that training with robotic rehabilitation devices is at least as effective as conventional physiotherapy. Further clinical studies are required in order to define the most appropriate robotic technical features based on the task, patients’ type, and degree of impairment.

Wearable systems open new perspectives for rehabilitation in individuals with disabilities, which can lead to difficulty in walking or making arm movements since they could be used to facilitate independent training in the clinic or at home. Wearable systems range from complex rigid exoskeleton structures for the assistance of joints or limbs to hybrid, soft, and interactive systems. The existing solutions are not yet widely used in clinical environments. The aim of  Chapter 17 is to review the scientific challenges and the current developments of wearable systems and to discuss their clinical potential.

Robots Not Only for Stroke Rehabilitation

Although most applications of robot rehabilitation focus on stroke and traumatic brain injury, these devices may find application in the treatment of other pathologies.

Chapter 18 addresses robot-assisted rehabilitation in multiple sclerosis (MS). Robot-assisted training leads to improved movement quality on reaching tasks, but clinical effects on standard assessment have not been always observed after multiple-session training. An increasing number of studies report effects of a multiple-week training program, but the magnitude of the effect was often similar to conventional training programs. Overall, there is evidence supporting the beneficial effect of robot- and technology-supported training, but its superiority compared with other or conventional treatment programs is still debatable. Research investigating the impact of different technological settings and the motor learning strategies implemented in technology must be encouraged for MS patients.

Persons with cognitive deficits are a completely different target population that can be addressed by therapy robots. Cognitive rehabilitation therapy (CRT) is a set of interventions designed to enhance cognitive performance. Ideally, CRT engages the participant in a learning activity to enhance neurocognitive skills relevant to the overall recovery goals. There is ongoing research to identify the determinants of a positive response to treatment.  Chapter 19 addresses the use of rehabilitation robots, socially interactive robots (SIR), and socially assistive robots (SAR), both virtual and embodied, to enhance, restore, or prevent early deterioration of cognitive abilities related to neurodegenerative disease or injury.

Integrating Robot Therapy With Neuro- and Psychophysiological Techniques

All the techniques and devices described until now use robot technology alone. Integration of different approaches and different technologies may improve the outcome, for instance, by training and restoring different functions within the same training session or by using physiological signals to monitor and/or control the recovery process. The following chapters focus on the use of neuro- and psychophysiological signals to enhance or complement robot-assisted therapy.

Chapter 20 presents hybrid FES-robot devices for training of activities of daily living aiming at the parallel restoration of functions by the external activation of paralyzed muscles and external mechanical support of postural functions. The combination of two modalities within the same treatment may multiply their individual effects as the external activation of muscles eliminates the need for large mechanical actuators and reduces the number of degrees of freedom to a controllable domain and, on the other hand, robot guidance removes the need for prolonged, fatiguing stimulation of muscles.

In spite of the acknowledged importance of proprioception for motor control and neuromotor rehabilitation, no effective method for assessment and rehabilitation of proprioceptive deficits has emerged in clinical practice. While there are many clinical scales for assessing proprioception, they all have insufficient psychometric properties and cannot be used in closed-loop treatment paradigms wherein treatment parameters are monitored and adjusted online or with a trial-by-trial frequency.  Chapter 21 discusses how robots can simultaneously address two interrelated needs: to provide sensitive and repeatable assessments of proprioceptive integrity and to automate repetitive training procedures designed to enhance proprioception and its contributions to functional movement.

The outcome of a training program can be conditioned not only by the patient’s physical conditions but also by his/her psychophysiological state during the whole course of the rehabilitation program.  Chapter 22 reviews psychophysiological response modalities that, together with task performance parameters and biomechanical measurements, may be used in a biocooperative approach to rehabilitation. The chapter focuses in particular on electrocardiogram, skin conductance, respiration signal, and peripheral skin temperature. Each signal is described in terms of acquisition modalities, signal processing, and features extraction. The psychophysiological responses in the case of multimodal challenge and physical activity are also examined, with reference to the differentiation of arousal and valence.

Understanding the mechanisms underlying muscle coordination during daily motor activities is a fascinating challenge in neuroscience and may provide important information pertaining to the recovery strategies of the neuromuscular system. Muscle synergies have been hypothesized as a neural strategy to simplify the control of the redundant motor actuators leading human movement and as a method to study motor coordination in healthy and neurological subjects.  Chapter 23 presents the theoretical framework for the extraction and the description of muscle synergies. Moreover, it summarizes how neuropathologies impact on muscle synergies and their potential for neurorehabilitation. Finally, it discusses how muscle synergies can be used to assess the effectiveness of robot-aided rehabilitation and the design of innovative control strategies.

Robots and Information Technologies Advances Toward Long-Term Intervention

As the world’s population ages, the management of chronic diseases will become more important. This shift will put pressure on health-care systems that often focus on providing effective care while reducing costs. The use of technological advancements to augment health-care services provides a method to meet these demands. Telerehabilitation robotics, addressed in  Chapter 24, combines established features of robot-assisted rehabilitation and tele-health care to provide distance rehabilitation services. While there is a growing market of robotic devices used in traditional rehabilitation settings, home-based implementations provide a unique set of challenges (e.g., remote monitoring, deployment constraints, and data management) that has limited the number of successful solutions. Clinical and kinematic outcomes show promising results and support further investigation. Cost analyses have demonstrated that telerehabilitation robotics is a cost-effective alternative compared with clinic-based therapy. While telerehabilitation robotics is a promising addition to conventional care, numerous barriers that limit practical integration will need to be addressed to allow a more widespread acceptance and use of this approach in rehabilitation.

As a final remark, robot rehabilitation involving an interactive high-intensity, intention-driven therapy based on motor learning principles and assist-as-needed leads to better outcomes than usual care in acute/subacute, chronic stroke and other pathologies. For this reason, clinical guidelines recommend the application of these technologies for the recovery of the lost functions.

This book highlights the most important technical aspects and strategies for the design, development, and application of robot technologies for rehabilitation purposes. With their ability to adapt exercise parameters based on physiological signals, objective and sensitive metrics reflecting the state and performance of a patient, the unique possibility to combine motor and somatosensory training, and the perspective of simple and wearable tools for home rehabilitation, robot devices promise further potential for the rehabilitation of neurological patients aiming at an improved motor function, a reduction of their disability, and overall an improved quality of life.


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[BOOK] White Book on Physical and Rehabilitation Medicine in Europe. Introductions, Executive Summary, and Methodology. – Full Text PDF

The White Book (WB) of Physical and Rehabilitation Medicine (PRM) in Europe is produced by the 4 EuropeanPRM Bodies (European Academy of Rehabilitation Medicine – EARM, European Society of PRM – ESPRM, European Union of Medical Specialists – PRM Section, European College of PRM-ECPRM served by the European Union of Medical Specialists-PRM Board) and constitutes the reference book for PRM physicians in Europe. It has now reached its third edition; the first was published in 1989 and the second in 2006/2007. The WB has multiple purposes, including providing a unifying framework for European countries, to inform decision-makers on European and national level, to offer educational material for PRM trainees and physicians and information about PRM to the medical community, other rehabilitation professionals and the public. The WB states the importance of PRM, a primary medical specialty that is present all over Europe, with a specific corpus disciplinae, a common background and history throughout Europe. PRM is internationally recognized and a partner of major international bodies, including the World Health Organization (WHO). PRM activities are strongly based on the documents of the United Nations (UN) and WHO, such as the Convention of the Rights of Persons with Disabilities (2006), the World Report on Disability (2011), the WHO Global Disability Action Plan 2014-2021 (2014) and the WHO initiative “Rehabilitation 2030: a call for action” (2017). The WB is organized in 4 sections, 11 chapters and some appendices. The WB starts with basic definitions and concepts of PRM and continues with why rehabilitation is needed by individuals and society. Rehabilitation focuses not only on health conditions but also on functioning. Accordingly, PRM is the medical specialty that strives to improve functioning of people with a health condition or experiencing disability. The fundamentals of PRM, the history of the PRM specialty, and the structure and activities of PRM organizations in Europe are presented, followed by a thorough presentation of the practice of PRM, i.e. knowledge and skills of PRM physicians, the clinical field of competence of PRM, the place of the PRM specialty in the healthcare system and society, education and continuous professional development of PRM physicians, specificities and challenges of science and research in PRM. The WB concludes with the way forward for the specialty: challenges and perspectives for the future of PRM.

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[BOOK] Epilepsy Across the Spectrum – NCBI Bookshelf

Cover of Epilepsy Across the Spectrum

Epilepsy Across the Spectrum

Promoting Health and Understanding

Institute of Medicine (US) Committee on the Public Health Dimensions of the Epilepsies; Editors: Mary Jane England, Catharyn T Liverman, Andrea M Schultz, and Larisa M Strawbridge.

Washington (DC): National Academies Press (US); 2012.

ISBN-13: 978-0-309-25506-6


Throughout this report, the committee emphasizes the ways in which epilepsy is a spectrum disorder. Epilepsy comprises more than 25 syndromes and many types of seizures that vary in severity. Additionally, people who have epilepsy span a spectrum that includes men and women of all ages and of all socioeconomic backgrounds and races/ethnicities, who live in all areas of the United States and across the globe. The impacts on physical health and quality of life encompass a spectrum as well, with individuals experiencing different health outcomes and having a range of activities of daily living that may be affected, including driving, academic achievement, social interactions, and employment. For some people, epilepsy is a childhood disorder that goes into remission (although the seizures may have lifelong consequences), while for others it is a lifelong burden or a condition that develops later in life or in response to an injury or other health condition. These many complexities of epilepsy make it a challenging health condition to convey to the general public to promote understanding and alleviate stigma. This report aims to provide evidence and impetus for actions that will improve the lives of people with epilepsy and their families.


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[BOOK] Emerging Therapies in Neurorehabilitation II – [Chapter] Virtual Rehabilitation – Request PDF


This chapter addresses the current state of the art of virtual rehabilitation by summarizing recent research results that focus on the assessment and remediation of motor impairments using virtual rehabilitation technology. Moreover, strengths and weaknesses of the virtual rehabilitation approach and its technical and clinical implications will be discussed. This overview is an update and extension of a previous virtual rehabilitation chapter with a similar focus. Despite tremendous advancements in virtual reality hardware in the past few years, clinical evidence for the efficacy of virtual rehabilitation methods is still sparse. All recent meta-analyses agree that the potential of virtual reality systems for motor rehabilitation in stroke and traumatic brain injury populations is evident, but that larger clinical trials are needed that address the contribution of individual aspects of virtual rehabilitation systems on different patient populations in acute and chronic stages of neurorehabilitation.

Virtual Rehabilitation | Request PDF. Available from:

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[BOOK] Emerging Therapies in Neurorehabilitation II – Βιβλία Google

José L. PonsRafael RayaJosé González
Springer30 Οκτ 2015 – 318 σελίδες

This book reports on the latest technological and clinical advances in the field of neurorehabilitation. It is, however, much more than a conventional survey of the state-of-the-art in neurorehabilitation technologies and therapies. It was written on the basis of a week of lively discussions between PhD students and leading research experts during the Summer School on Neurorehabilitation (SSNR2014), held September 15-19 in Baiona, Spain. Its unconventional format makes it a perfect guide for all PhD students, researchers and professionals interested in gaining a multidisciplinary perspective on current and future neurorehabilitation scenarios. The book addresses various aspects of neurorehabilitation research and practice, including a selection of common impairments affecting CNS function, such as stroke and spinal cord injury, as well as cutting-edge rehabilitation and diagnostics technologies, including robotics, neuroprosthetics, brain-machine interfaces and neuromodulation.

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[BOOK Chapter] Functional Electrical Stimulation and Its Use During Cycling for the Rehabilitation of Individuals with Stroke – Abstract+References

Advanced Technologies for the Rehabilitation of Gait and Balance DisordersAbstract

Stroke disease involves an increasing number of subjects due to the aging population. In clinical practice‚ the presence of widely accessible rehabilitative interventions to facilitate the patients’ motor recovery‚ especially in the early stages after injury when wider improvement can be gained‚ is crucial to reduce social and economical costs. The functional electrical stimulation (FES) has been investigated as a tool to promote locomotion ability in stroke patients. Particular attention was given to FES delivered during cycling‚ which is recognized as a safe and widely accessible way to provide a FES-based rehabilitative intervention in the most impaired subjects. In this chapter the neurophysiological basis of FES and its potential correlates to facilitate the long-term reorganization at both cortical and spinal level have been discussed. A discussion on clinical evidence and possible future direction is also proposed.


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[BOOK Chapter] The “Arm” Line of Devices for Neurological Rehabilitation: Engineering Book Chapter – Abstract


In the modern scenario of neurological rehabilitation, which requires affordable solutions oriented toward promoting home training, the Institute of Industrial Technologies and Automation (ITIA) of the Italian National Research Council (CNR) developed a line of prototypal devices for the rehabilitation of the upper limb, called “Arm.” Arm devices were conceived to promote rehabilitation at affordable prices by capturing all the main features of the state-of-the-art devices. In fact, Arm devices focus on the main features requested by a robot therapist: mechanical adaptation to the patient, ranging from passive motion to high transparency, assist-as-needed and resistive modalities; proper use of sensors for performance monitoring; easy-to-use, modular, and adaptable design. These desirable features are combined with low-cost, additive manufacturing procedures, with the purpose of meeting the requirements coming from research on neuro-motor rehabilitation and motor control and coupling them with the recent breakthrough innovations in design and manufacturing.

The “Arm” Line of Devices for Neurological Rehabilitation

Copyright: © 2018 |Pages: 30

DOI: 10.4018/978-1-5225-2993-4.ch007




 The use of robotic devices for upper-limb neuro-motor rehabilitation is usual practice in clinical centers. In respect to conventional therapies, robots allow to increase training intensity and help patients to promote their active contribution. Furthermore, robots can act as measurers of patients’ performances and adapt their interaction modalities to the emerging needs during the rehabilitation course. Robots like ARMin, MIT Manus, Armeo Spring, Braccio di Ferro, represent the state of the art devices for rehabilitation of the upper-limb and for promoting motor recovery. According to the available assessments and studies in the literature, their efficacy is slightly/moderately higher than the one of conventional therapies. Furthermore, robots are used in research to learn more about physiological and pathological motor control and neuromuscular diseases. Unfortunately, while being the state of the art devices for neuro-motor stimulation and training, such robots are very expensive and not compliant to user-friendly requirements that are needed for semi-autonomous home use. Consequently, they can be used only in clinical environments, under the supervision of medical personnel. Furthermore, sanitary costs related to rehabilitation are increasing and clinical centers can hardly support their burden. The possibility of delocalizing rehabilitation from clinical centers opens the chance for training performed in home environment, with time and costs savings for both the sanitary system and patients. In this scenario, which requires affordable solutions oriented toward promoting home training, the Institute of Industrial Technologies and Automation (ITIA) of the Italian National Research Council (CNR) developed a line of prototypal devices for the rehabilitation of the upper-limb, called -ArmArm devices were conceived to test the possibility of promoting rehabilitation at affordable prices but capturing all the main features of the state of the art devices. In fact, Arm devices focus on the main features requested by a robot therapist: mechanical adaptation to the patient, ranging from passive motion to high transparency, assist-as-needed and resistive modalities; proper use of sensors for performance monitoring; easy-to-use, modular and adaptable design. These desirable features are combined with low-cost, additive manufacturing procedures, with the purpose of meeting the requirements coming from research on neuro-motor rehabilitation and motor control and coupling them with the recent breakthrough innovations in design and manufacturing. Arm devices cover both clinical and home-oriented training and are designed for adaptation to patients with different motor impairment.

The Arm prototypes are:

  • • LINarm: linear device, freely orientable in space, suitable for functional movements. It features a variable stiffness actuation, allowing to adapt the mechanical behavior of the device to patients’ needs. Functional Electrical Stimulation, simple Virtual Environments and a Patient Model, gathering data from integrated sensors and modulating the level of assistance, are integrated in the set-up. The LINarm++ Echord++ Project ended in October 2016 and guided the development of a second, more refined prototype, enhancing the original concept.
  • • PLANarm: planar device, freely orientable in space, suitable for planar functional movements. The state of the art planar robots used in literature for motor control and motor learning research inspired PLANarm. It features a variable stiffness actuation, allowing adapting the mechanical behavior of the device depending on patients’ needs.
  • • DUALarm: Low-Cost device for bimanual rehabilitation, exploiting the capability of the less affected limb to provide rehabilitation to the more affected limb. DUALarm is completely realized in 3D printing technology and aims at being an easy-to-use, low-cost, open-source project. Currently, reaching movements can be trained, but the device is conceived to be suitable for training of other functional gestures.
  • • LIGHTarm: Exoskeleton for the rehabilitation of the upper-limb, designed in two versions: LIGHTarm, not actuated, and conceived to support the weight of the impaired limb. The mechanical design includes high backdrivability, focusing on shoulder rhythm and elbow singular configurations.
  • • VIRTUALarm: Kinect One-based platform for motor monitoring, including body and limb tracking and a biomechanical evaluation of the performance in relation to databases of healthy subjects. Assessments include range of motion, motion dynamics, effort, motor control indexes, body segments barycenter tracking.

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[BOOK] Integrative Psychiatry and Brain Health – Google Books

Front Cover

Daniel A. MontiAndrew B. NewbergAndrew Weil
Oxford University Press, 2018 – Medical – 616 pages
Integrative Medicine is an emerging discipline that not only bridges the existing disciplines of psychiatry psychology, but provides a scientifically-based framework that synthesizes the rest of physiology, biochemistry and other health dimensions such as social support and spirituality, which collectively contribute to brain and body health and overall well-being. Patients who have not tolerated or not responded optimally to traditional treatments are also good candidates for integrative approaches. This new edition of Integrative Psychiatry and Brain Health reflects the tremendous advances in science that allude to mechanisms of action that weave together seemingly unrelated disciplines for the promotion of health and wellness.Part of the Weil Integrative Medicine Library, this volume provides a rational and evidence-based approach to the integrative therapy of mental disorders, integrating the principles of alternative and complementary therapies into the principles and practice of conventional psychiatry and psychology. Integrative Psychiatry and Brain Health examines what works and what doesn’t, and offers practical guidelines for physicians to incorporate integrative medicine into their practice and to advise patients on reasonable and effective therapies. The text discusses areas of controversy and identifies areas of uncertainty where future research is needed. Chapters also cite the best available evidence for both the safety and the efficacy of all therapies discussed. The information is presented in accessible and easy-to-read formats, including clinical pearls and key points.

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