Posts Tagged DLPFC

[ARTICLE] Transcranial Direct Current Stimulation Modulates Neuronal Activity and Learning in Pilot Training – Full Text HTML

Skill acquisition requires distributed learning both within (online) and across (offline) days to consolidate experiences into newly learned abilities. In particular, piloting an aircraft requires skills developed from extensive training and practice. Here, we tested the hypothesis that transcranial direct current stimulation (tDCS) can modulate neuronal function to improve skill learning and performance during flight simulator training of aircraft landing procedures.

Thirty-two right-handed participants consented to participate in four consecutive daily sessions of flight simulation training and received sham or anodal high-definition-tDCS to the right dorsolateral prefrontal cortex (DLPFC) or left motor cortex (M1) in a randomized, double-blind experiment. Continuous electroencephalography (EEG) and functional near infrared spectroscopy (fNIRS) were collected during flight simulation, n-back working memory, and resting-state assessments. tDCS of the right DLPFC increased midline-frontal theta-band activity in flight and n-back working memory training, confirming tDCS-related modulation of brain processes involved in executive function. This modulation corresponded to a significantly different online and offline learning rates for working memory accuracy and decreased inter-subject behavioral variability in flight and n-back tasks in the DLPFC stimulation group. Additionally, tDCS of left M1 increased parietal alpha power during flight tasks and tDCS to the right DLPFC increased midline frontal theta-band power during n-back and flight tasks.

These results demonstrate a modulation of group variance in skill acquisition through an increasing in learned skill consistency in cognitive and real-world tasks with tDCS. Further, tDCS performance improvements corresponded to changes in electrophysiological and blood-oxygenation activity of the DLPFC and motor cortices, providing a stronger link between modulated neuronal function and behavior.

Continue —> Frontiers | Transcranial Direct Current Stimulation Modulates Neuronal Activity and Learning in Pilot Training | Frontiers in Human Neuroscience

Figure 1. Experimental design. (A) Experiment timeline depicting the relative timing of each task (see Table 1 for descriptions of each task). The N-Back and Easy Landing tasks are highlighted, and the duration of tDCS is depicted in red. (B) An example of 6 trials of the N-Back task is shown. 1-back orientation and location match trials are highlighted in yellow. (C) The flight simulator, neuroimaging (EEG and FNIRS) and tDCS setup is shown with on a subject (1). Flight simulator equipment includes three-panel display, a radio panel (2), an instrument panel (3) with (from left to right) compass, altimeter, airspeed indicator, vertical speed indicator, and turn/slip indicator, a multi-panel (4) with (from left to right) autopilot settings, auto throttle switch, flaps switch, and elevator trim wheel, yoke (5), and throttle quadrant system (6). (D) Autopilot flight path for the Easy Landing task is shown in 3 dimensions, color-coded by vertical speed. Screenshots for initial descent, approach, and landing are also shown.

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[WEB SITE] Magstim’s Repetitive Transcranial Magnetic Stimulation Therapy System FDA Cleared to Fight Major Depression (VIDEO)


The FDA awarded Magstim, a Carmarthenshire, Wales firm, clearance to bring to market the company’s Magstim Rapid2 rTMS (repetitive Transcranial Magnetic Stimulation) Therapy System. The system is indicated to treat drug resistant major depressive disorder in an outpatient setting.

The Magstim Rapid2 has been available to researchers in fields such as cognitive neuroscience, neurophysiology, and rehabilitation. Now the magnetic stimulator will be available in the U.S. as a clinical product.

It’s intended to target the dorsolateral left pre-frontal cortex (DLPFC), a region of the brain that sees reduced blood flow in patients with serious depression. When magnetically stimulated, blood flow tends to increase, improving mood and reducing symptoms of the depression.

Here’s Robin Davies, the CEO of Magstim, talking about the Rapid2 rTMS system:

via Magstim’s Repetitive Transcranial Magnetic Stimulation Therapy System FDA Cleared to Fight Major Depression (VIDEO).

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