Posts Tagged mCIMT

[Abstract] Functional outcome, Rehabilitation, Upper extremity function

Abstract

Introduction: Paretic upper limb in stroke patients has a significant impact on the quality of life. Modified Constraint Induced Movement Therapy (mCIMT) is one of the treatment options used for the improvement of the function of the paretic limb.

Aim: To investigate the efficacy of four week duration mCIMT in the management of upper extremity weakness in hemiparetic patients due to stroke.

Materials and Methods: Prospective single blind, parallel randomized controlled trial in which 30 patients received conventional rehabilitation programme (control group) and 30 patients participated in a mCIMT programme in addition to the conventional rehabilitation programme (study group). The mCIMT included three hours therapy sessions emphasizing the affected arm use in general functional tasks, three times a week for four weeks. Their normal arm was also constrained for five hours per day over five days per week. All the patients were assessed at baseline, one month and three months after completion of therapy using Fugl-Meyer Assessment (FMA) score for upper extremity and Motor Activity Log (MAL) scale comprising of Amount of Use (AOU) score and Quality of Use (QOU) score.

Results: All the 3 scores improved significantly in both the groups at each follow-up. Post-hoc analysis revealed that compared to conventional rehabilitation group, mCIMT group showed significantly better scores at 1 month {FMA1 (p-value <0.0001, es0.2870), AOU1 (p-value 0.0007, es0.1830), QOU1 (p-value 0.0015, es0.1640)} and 3 months {FMA3 (p-value <.0001, es0.4240), AOU3 (p-value 0.0003, es 0.2030), QOU3 (p-value 0.0008, es 0.1790)}.

Conclusion: Four weeks duration for mCIMT is effective in improving the motor function in paretic upper limb of stroke patients.

Source: JCDR – Functional outcome, Rehabilitation, Upper extremity function

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[Abstract] Efficacy of modified constraint-induced movement therapy in acute stroke

BACKGROUND: Modified constraint induced movement therapy (m-CIMT) discourages the use of the unaffected extremity and encourages the active use of the hemiplegic arm in order to restore the motor function. AIM: The aim was to assess the efficacy of m-CIMT on functional recovery of upper extremity (UE) in acute stroke patients, as compared to conventional rehabilitation therapy.

DESIGN: This is a prospective comparative study.

SETTING: This study included sixty patients with acute stroke recruited from neurology department.

METHODS: This study included sixty acute stroke patients. Inclusion criteria were: patients within two weeks from the onset of stroke, persistent hemiparesis leading to impaired upper extremity function, evidence of preserved cognitive function, and a minimum of 10 degrees of active finger extension and 20 degrees of active wrist extension. Exclusion criteria were: intra-cerebral hemorrhage, previous stroke on the same side, presence of neglect or a degree of aphasia impeding understanding of instructions, and conditions that limit the use of the upper limb before the stroke. Patients were assessed by Fugl-Meyer motor assessment (FMA), action research arm test (ARAT) and motor evoked potentials (MEPs), recorded from the abductor pollicis brevis (APB) of the affected hand. The clinical and neurophysiological tests were performed pre and postrehabilitation. The patients were divided into two groups: conventional rehabilitation program group (CRP) included 30 patients who were given a conventional rehabilitation program for two weeks. CIMT group included 30 patients who were subjected to modified CIMT for two consecutive weeks. Total treatment time was the same in both groups.

RESULTS: CRP group showed a non-significant improvement in FMA and ARAT. CIMT group showed a significant improvement in clinical scores on all tests (p < 0.05). When comparing both groups using FMA and ARAT tests pre- and post- therapy, a significant difference (p < 0.05) was found between both groups with CIMT group showing greater improvement. When comparing MEPs in CRP group, pre and postrehabilitation, a non-significant improvement was found for resting motor threshold (RMT), central motor conduction time (CMCT) and amplitude of MEPs. In contrast, each of the MEP parameters exhibited a significant improvement in CIMT group (p < 0.05).

CONCLUSION: In contrast to conventional rehabilitation therapy, modified CIMT revealed a significant functional and MEP improvement in acute stroke patients indicating that m-CIMT might be a more efficient treatment strategy.

CLINICAL REHABILITATION IMPACT: It is advised to use modified constraint movement therapy in rehabilitation of cerebrovascular stroke during acute stage.

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Source: PEDro – Search Detailed Search Results

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[ARTICLE] Constraint-Induced Movement Therapy in Compared to Traditional Therapy in Chronic Post-stroke patients – Full Text PDF

Abstract

Introduction: Constraint-induced movement therapy (CIMT) forces the use of the affected side by restraining the unaffected side. The purpose of this article is to explore the changes of motor and functional performance after modified CIMT (mCIMT) in comparison with traditional rehabilitation (TR) in chronic post-stroke patients.

Material and Methods: A total of 12 patients randomly assigned into two treatment groups. Six patients in the mCIMT group received intensive training in a more affected limb for 2 hours daily, 5 days/week using shaping method over a period of 21 days. Participants less affected limb were restrained in arm – hand splint with a target of wearing it for 5 hours daily. The patients in TR group received bimanual and unilateral activities, stretching, strengthening and coordination exercises of the impaired side, tone modification and coordination exercises of the affected side. The focus was to increase independence in activities of daily living activities using affected side. The motor activity log (MAL), wolf motor function test (WMFT), and modified ashworth scale were measured at pre-test (1 day before training), posttest (1 day after training) and follow-up in 3 weeks after training.

Results: The Friedman test found significant differences between pre-test, post-test, and follow-up in MAL and WMFT in mCIMT group. Furthermore, mCIMT group showed significant decreased spasticity (P = 0.030) that measured by ash worth scale. The effect sizes between post-test and pre-test in the above-mentioned outcome measures were moderate to large in mCIMT, ranging from 0.3 to 0.76, but in TR group the effect size were small, ranging from 0 to 0.2.

Conclusion: Therefore, it seems that the mCIMT treatment was more effective than TR in improving some parameters.

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[ARTICLE] Adherence to modified constraint-induced movement therapy: the case for meaningful occupation – Full Text

Abstract

INTRODUCTION: Modified constraint-induced movement therapy (mCIMT) has been shown to improve function of an affected upper limb post stroke. However, factors influencing adherence of individuals undertaking a mCIMT protocol require further investigation.

AIM: To explore the experience of two participants undergoing a mCIMT protocol and examine factors influencing adherence to the protocol.

METHODS: A qualitative case study design was used. Two participants with upper limb hemiparesis following a stroke were recruited and received mCIMT (two hours of therapy, three days per week for a total of two weeks). During the treatment period, participants were also encouraged to wear the restraint mitt for four hours per day at home.

RESULTS: Participants reported increased confidence and self-esteem following participation, as well as improvements in bi-lateral upper limb function. Participants reported the mCIMT protocol as being highly frustrating. However, motivation to adhere to the protocol was positively influenced by the meaningfulness of the occupations attempted.

CONCLUSION: Although mCIMT can prove frustrating, meaningful occupations may act as a powerful motivator towards adherence to a mCIMT protocol. Further research is required.

WHAT GAP THIS FILLS

What is already known: The literature on the effectiveness of constraint-induced movement therapy (CIMT) and its modifications (mCIMT), to improve motor issues post stroke, is broad and conclusive. However, the demands and rigor of CIMT or mCIMT can influence compliance negatively.
What this study adds: This study offers an insight into the experience of undergoing mCIMT. In relation to client motivation and adherence to protocol, it highlights the importance of meaningful and psychologically rewarding occupations.

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[ARTICLE] Effects of Unilateral Upper Limb Training in Two Distinct Prognostic Groups Early After Stroke – Full Text

Abstract

Background and Objective. Favorable prognosis of the upper limb depends on preservation or return of voluntary finger extension (FE) early after stroke. The present study aimed to determine the effects of modified constraint-induced movement therapy (mCIMT) and electromyography-triggered neuromuscular stimulation (EMG-NMS) on upper limb capacity early poststroke.

Methods. A total of 159 ischemic stroke patients were included: 58 patients with a favorable prognosis (>10° of FE) were randomly allocated to 3 weeks of mCIMT or usual care only; 101 patients with an unfavorable prognosis were allocated to 3-week EMG-NMS or usual care only. Both interventions started within 14 days poststroke, lasted up until 5 weeks, focused at preservation or return of FE.

Results. Upper limb capacity was measured with the Action Research Arm Test (ARAT), assessed weekly within the first 5 weeks poststroke and at postassessments at 8, 12, and 26 weeks. Clinically relevant differences in ARAT in favor of mCIMT were found after 5, 8, and 12 weeks poststroke (respectively, 6, 7, and 7 points; P < .05), but not after 26 weeks. We did not find statistically significant differences between mCIMT and usual care on impairment measures, such as the Fugl-Meyer assessment of the arm (FMA-UE). EMG-NMS did not result in significant differences.

Conclusions. Three weeks of early mCIMT is superior to usual care in terms of regaining upper limb capacity in patients with a favorable prognosis; 3 weeks of EMG-NMS in patients with an unfavorable prognosis is not beneficial. Despite meaningful improvements in upper limb capacity, no evidence was found that the time-dependent neurological improvements early poststroke are significantly influenced by either mCIMT or EMG-NMS.

Introduction

Several prospective cohort studies among stroke patients have shown that the functional outcome of the upper limb is largely defined within the first 5 weeks poststroke and is mainly driven by (yet poorly understood) mechanisms of spontaneous neurological recovery.1,2 Observational studies showed that the presence of some voluntary finger extension (FE) within 72 hours is a favorable indicator for the return of dexterity poststroke.3,4 This suggests that early control of FE is an important prognostic factor in stratifying patients for upper limb intervention trials early poststroke.2

For those with a favorable prognosis, indicated by some voluntary FE early poststroke, constraint-induced movement therapy (CIMT) or a modified version (mCIMT) may benefit arm-hand activities and self-reported hand function in daily life.5The number of phase II trials on mCIMT within the first days or weeks poststroke is however small and findings are rather inconclusive. For example, Dromerick et al6showed in a proof of concept trial that 1 or 2 hours mCIMT per working day for 2 weeks was not superior to an equal dosage of usual care, whereas a high dose of 3 hours mCIMT per working day resulted in less improvement on functional outcome measured with the Action Research Arm Test (ARAT) at 3 months poststroke.

For those with an unfavorable prognosis for functional outcome at 6 months, that is, patients without voluntary FE,1,3,4 no evidence-based therapies have been reported so far. In subacute and chronic stroke, innovative therapies such as electromyography-triggered neuromuscular stimulation (EMG-NMS) of the finger extensors to improve voluntary control have shown promise in terms of increasing active range of motion.711 Furthermore, several studies suggest that EMG-NMS may produce changes in cortical activation patterns and excitability in chronic stroke.12,13 For example, Shin et al13 showed in a small proof of concept trial (n = 14) that a daily 30-minute program for 10 weeks shifted cortical activation patterns as seen in functional magnetic resonance imaging from the ipsilateral sensorimotor cortex to the contralateral sensorimotor cortex in chronic stroke. Despite the growing evidence for enhanced levels of homeostatic neuroplasticity in the first weeks poststroke,14 early started EMG-NMS trials for patients without FE are lacking in this restricted time window.

The first objective of the present study was to investigate the effects of an early mCIMT program on recovery of upper limb capacity during the first 6 months, starting within 14 days poststroke in patients with some voluntary FE. Our second objective was to investigate the effects of early EMG-NMS on the recovery of voluntary FE and upper limb capacity during the first 6 months, starting within 14 days poststroke in patients with no voluntary control of the finger extensors. We hypothesized that an intensive 3-week mCIMT program would result in a clinically meaningful improvement in ARAT scores compared with usual care alone. For the patients with an unfavorable prognosis we hypothesized that a higher percentage of patients (10% or more increase) would regain some dexterity (ARAT score >9 points on a maximum of 57 points) if they received intensive daily EMG-NMS for 3 weeks, compared with usual care alone.

Continue —>  Effects of Unilateral Upper Limb Training in Two Distinct Prognostic Groups Early After Stroke

 

Figure 1. Inclusion flow diagram. The total amount of patients with cerebrovascular accidents was estimated using the number of admitted patients in each participating center. mCIMT: modified constrained-induced movement therapy; EMG-NMS, electromyography-triggered neuromuscular stimulation.

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[ARTICLE] Effectiveness of Modified Constraint Induced Movement Therapy and Bilateral Arm Training on Upper Extremity Function after Chronic Stroke: A Comparative Study – Full Text PDF

ABSTRACT

Statement of the Problem: Upper limb hemiparesis is a common impairment underlying disability after Stroke. Transfer of treatment to daily functioning remains a question for traditional approaches used in treatment of upper extremity hemiparesis. Approaches based on Motor Learning principles may facilitate the transfer of treatment to activities of daily living.
Methodology: Forty one subjects with chronic stroke, attending department of occupational therapy, National Institute for the Orthopaedically Handicapped, Kolkata, West Bengal, India participated in a single blinded randomized pre-test and post-test control group training study. Subjects were randomized over three intervention groups receiving modified Constraint Induced Movement Therapy (n = 13), Bilateral Arm training (n = 14), and an equally intensive conventional treatment program (n = 14). Subjects in the bilateral arm training group participated in bilateral symmetrical activities, where as subjects in constraint induced movement therapy group performed functional activities with the affected arm only and conventional group received conventional Occupational Therapy. Each group received intensive training for 1 hour/day, 5 days/week, for 8 weeks. Pre-treatment and post-treatment measures included the Fugl-Meyer measurement of physical performance (FMA- upper extremity section), action research arm test, motor activity log. Assessments were administered by a rater blinded to group assignment.
Result: Both m-CIMT (p = 0.01) and bilateral arm training (p = 0.01) group showed statistically significant improvement in upper extremity functioning on Action Research Arm Test score in comparison to the conventional therapy group (p = 0.33). The bilateral arm training group had significantly greater improvement in upper arm function (Proximal Fugl-Meyer Assessment score, p = 0.001); while the constraint induced movement therapy group had greater improvement of hand functions (Distal Fugl-Meyer Assessment score, p = 0.001. There is an improvement seen in Quality of movement in the Conventional Therapy group. (p = 0.001).
Conclusion: Both the treatment techniques can be used for upper extremity management in patients with chronic stroke. Bilateral arm training may be used to improve upper arm function and m-CIMT may be used to improve hand functions, while the group that received modified constraint induced movement therapy had greater improvement.

References

[1] Whittal, J., McCombe Waller, S., Silver, K.H.C., et al. (2000) Repetitive Bilateral Arm Training with Rhythmic Auditory Cueing Improves Motor Function in Chronic Stroke. Stroke, 31, 2390-2395.
http://dx.doi.org/10.1161/01.STR.31.10.2390
[2] Bonifer, N.M., Anderson, K.M., Arciniegas, D.B., et al. (2005) Constraint Induced Movement Therapy for Stroke: Efficacy for Patients with Minimal Upper Extremity Motor Ability. Archives of Physical Medicine and Rehabilitation, 86, 1867-1872. http://dx.doi.org/10.1016/j.apmr.2005.04.002
[3] Radomski, M.V. and Trombly Latham, C.A. (2008) Occupational Therapy for Physical Dysfunction. 6th Edition, Lippincott Williams and Wilkins, Philadelphia.
[4] Taub, E., Uswatte, G. and Pidikiti, R. (1999) Constraint Induced Movement Therapy, a New Family of Techniques with Broad Application to Physical Rehabilitation—A Clinical Review. Journal of Rehabilitation Research and Development, 36, 273-251.
[5] Dobkin, B.H. (2005) Clinical Practice. Rehabilitation after Stroke. The New England Journal of Medicine, 352, 1677- 1684. http://dx.doi.org/10.1056/NEJMcp043511
[6] Taub, E., et al. (1993) Techniques to Improve Chronic Motor Deficits after Stroke. Archive of Physical Medicine and Rehabilitation, 74, 347-354.
[7] Page, S.J., Levine, P., Sisto, S., et al. (2002) Stroke Patients and Therapists Opinions of Constraint Induced Movement Therapy. Clinical Rehabilitation, 16, 55-60. http://dx.doi.org/10.1191/0269215502cr473oa
[8] Page, S.J., Sisto, S., Levine, P. and McGrath, R.E. (2004) Efficacy of Modified Constraint Induced Movement Therapy in Chronic Stroke: A Single Blind Randomized Controlled Trial. Archives of Physical Medicine and Rehabilitation, 85, 14-17. http://dx.doi.org/10.1016/S0003-9993(03)00481-7
[9] Luft, A.R., McCombe-Waller, S., Whitall, J. et al. (2004) Repetitive Bilateral Arm Training and Motor Cortex Activation in Chronic Stroke. JAMA, 292, 1853-1861. http://dx.doi.org/10.1001/jama.292.15.1853
[10] Uswatte, G. and Taub, E. (1999) Constraint Induced Movement Therapy. New Approaches to Outcome Measurement in Rehabilitation. In: Struss, D.T., Winocur, G. and Robertson, I.H., Eds., Cognitive Neurorehabilitation, a Comprehensive Approach, Cambridge University Press, Cambridge, England, 215-29
[11] Fugl-Meyer, A.R., et al. (1975) The Post Stroke Hemiplegic Patient. I. A Method for Evaluation of Physical Performance. Scandinavian Journal of Rehabilitation Medicine, 7, 13-31.
[12] Vander Lee, J.H., Beckermen, H., Lankhorst, G.J. and Breter, L.M. (2001) The Responsiveness of the Action Research Arm Test and Fugl-Meyer Assessment of Physical Performance Scale in Chronic Stroke Patients. Journal of Rehabilitation Medicine, 33, 110-113.
http://dx.doi.org/10.1080/165019701750165916
[13] Vander Lee, J.H., Wagenaar, R.C., Lankhorst, G.J., et al. (1999) Forced Use of the Upper Extremity in Chronic Stroke Patients: Results from a Single Blind Randomized Clinical Trial. Stroke, 30, 2369-2375.
http://dx.doi.org/10.1161/01.STR.30.11.2369
[14] Staines, W.R., McIlroy, W.E., Graham, S.J. and Black, S.E. (2001) Bilateral Movement Enhances Ipsilesional Cortical Activity in Acute Stroke: A Pilot Functional MRI Study. Neurology, 56, 401-404.
http://dx.doi.org/10.1212/WNL.56.3.401
[15] Kelso, J.A.S., Putnam, C.A. and Goodman, D. (1983) On the Space-Time Structure of Human Inter Limb Coordination. The Quarterly Journal of Experimental Psychology Section, 35A, 347-375.
http://dx.doi.org/10.1080/14640748308402139
[16] Carr, J. and Shepherd, R. (1998) Neurological Rehabilitation: Optimizing Motor Performance. Butterworth-Heineman, Edinburgh, 241-264.
[17] Levine, P. and Page, S.J. (2004) Modified Constraint Induced Movement Therapy: A Promising Restorative out Patient Therapy. Top Stroke Rehabilitation, 11, 1-10.
http://dx.doi.org/10.1310/R4HN-51MW-JFYK-2JAN

Source: Effectiveness of Modified Constraint Induced Movement Therapy and Bilateral Arm Training on Upper Extremity Function after Chronic Stroke: A Comparative Study

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[Abstract] Effects of Unilateral Upper Limb Training in Two Distinct Prognostic Groups Early After Stroke

Abstract

Background and Objective. Favorable prognosis of the upper limb depends on preservation or return of voluntary finger extension (FE) early after stroke. The present study aimed to determine the effects of modified constraint-induced movement therapy (mCIMT) and electromyography-triggered neuromuscular stimulation (EMG-NMS) on upper limb capacity early poststroke.

Methods. A total of 159 ischemic stroke patients were included: 58 patients with a favorable prognosis (>10° of FE) were randomly allocated to 3 weeks of mCIMT or usual care only; 101 patients with an unfavorable prognosis were allocated to 3-week EMG-NMS or usual care only. Both interventions started within 14 days poststroke, lasted up until 5 weeks, focused at preservation or return of FE.

Results. Upper limb capacity was measured with the Action Research Arm Test (ARAT), assessed weekly within the first 5 weeks poststroke and at postassessments at 8, 12, and 26 weeks. Clinically relevant differences in ARAT in favor of mCIMT were found after 5, 8, and 12 weeks poststroke (respectively, 6, 7, and 7 points; P < .05), but not after 26 weeks. We did not find statistically significant differences between mCIMT and usual care on impairment measures, such as the Fugl-Meyer assessment of the arm (FMA-UE). EMG-NMS did not result in significant differences.

Conclusions. Three weeks of early mCIMT is superior to usual care in terms of regaining upper limb capacity in patients with a favorable prognosis; 3 weeks of EMG-NMS in patients with an unfavorable prognosis is not beneficial. Despite meaningful improvements in upper limb capacity, no evidence was found that the time-dependent neurological improvements early poststroke are significantly influenced by either mCIMT or EMG-NMS.

Source: Effects of Unilateral Upper Limb Training in Two Distinct Prognostic Groups Early After Stroke

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[Abstract] The efficacy of Wii-based Movement Therapy for upper limb rehabilitation in the chronic poststroke period: a randomized controlled trial

Background: More effective and efficient rehabilitation is urgently needed to address the prevalence of unmet rehabilitation needs after stroke. This study compared the efficacy of two poststroke upper limb therapy protocols.

Aims and/or hypothesis: We tested the hypothesis that Wii-based movement therapy would be as effective as modified constraint-induced movement therapy for post-stroke upper-limb motor rehabilitation.

Methods: Forty-one patients, 2–46 months poststroke, completed a 14-day program of Wii-based Movement Therapy or modified Constraint-induced Movement Therapy in a dose-matched, assessor-blinded randomized controlled trial, conducted in a research institute or patient’s homes. Primary outcome measures were the Wolf Motor Function Test timed-tasks and Motor Activity Log Quality of Movement scale. Patients were assessed at prebaseline (14 days pretherapy), baseline, post-therapy, and six-month follow-up. Data were analyzed using linear mixed models and repeated measures analysis of variance.

Results: There were no differences between groups for either primary outcome at any time point. Motor function was stable between prebaseline and baseline (P > 0·05), improved with therapy (P  0·05). Wolf Motor Function Test timed-tasks log times improved from 2·1 ± 0·22 to 1·7 ± 0·22 s after Wii-based Movement Therapy, and 2·6 ± 0·23 to 2·3 ± 0·24 s after modified Constraint-induced Movement Therapy. Motor Activity Log Quality of Movement scale scores improved from 67·7 ± 6·07 to 102·4 ± 6·48 after Wii-based Movement Therapy and 64·1 ± 7·30 to 93·0 ± 5·95 after modified Constraint-induced Movement Therapy (mean ± standard error of the mean). Patient preference, acceptance, and continued engagement were higher for Wii-based Movement Therapy than modified Constraint-induced Movement Therapy.

Conclusions: This study demonstrates that Wii-based Movement Therapy is an effective upper limb rehabilitation poststroke with high patient compliance. It is as effective as modified Constraint-induced Movement Therapy for improving more affected upper limb movement and increased independence in activities of daily living.

Source: The efficacy of Wii-based Movement Therapy for upper limb rehabilitation in the chronic poststroke period: a randomized controlled trial – McNulty – 2015 – International Journal of Stroke – Wiley Online Library

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[WEB SITE] New Acronyms in the Neurorehabilitation Literature; What Do They Mean? – Saebo

For those working in upper extremity (UE) neurorehabilitation, the acronyms CIMT (constraint induced movement therapy) and mCIMT (modified constraint induced movement therapy) are now very familiar.

CIMT is an intervention approach which involves restraint of the non-involved UE for 90% of waking hours over a two week period, to include weekends, with repetitive training of the involved UE using shaping principles for 6 hours per day on the weekdays (Kunkel, Kopp, Muller, Villringer, Villringer, Taub, & Flor, 1999).

mCIMT, a lower level of intensity of CIMT,  involves restraint of the non-involved UE for 5 hours per day during the weekdays along with three 30 minute sessions per week of shaping and standard task training of the involved UE for a 10 week period (Page, Levine, Leonard, Szaflarski, & Kissela, 2008).

Many will also be familiar with another acronym, the EXCITE trials. Wolf, Winstein, Miller, Taub, Uswatte, Morris, Giuliani, Light, and Nichols-Larsen (2006) completed the first ever national multi-site randomized clinical trial (RCT), the Extremity Constraint Induced Therapy Evaluation (EXCITE),  with 222 participants, to compare the effectiveness of CIMT versus usual customary care for individuals 3 to 6 months post stroke. The CIMT group demonstrated significant improvements in UE function and use both at 2 weeks and at a 12 month follow up compared to the control group (Wolf et al, 2006).

A review of the recent literature now reveals two additional acronyms that may not be so familiar, VECTORS and EXPLICIT.

Shannon Scott, OTR/L, is the Clinical Assistant Professor at Stony Brook University Southampton. She is a graduate of the University of British Columbia in Vancouver, Canada and is currently pursuing her doctorate in OT through Quinnipiac University. She has over 23 years of clinical experience, specializing in Neurorehabilitation. She is Level One Brain Injury Certified and is NDT trained. Shannon was one of the first 10 therapists trained in the use of Saebo. Prior to teaching at Stony Brook, Shannon was the Director of Clinical Services at Saebo.

Very early constraint-induced movement during stroke rehabilitation (VECTORS) was a single blind RCT comparing traditional UE therapy with high intensity CIMT during acute inpatient rehabilitation over a two week period (Dromerick, Lang, Birkenmeier, et al., 2009). This study demonstrated an inverse dose-response relationship where high dosed CIMT resulted in less motor improvement when applied in the early days after stroke (9.65 +/- 4.5 days).

There have been animal studies published that have shown early high intensity forced limb use has resulted in expansion of the lesioned area (Kozlowski, James, & Schallert, 1996). However, the VECTORS study found no MRI evidence of this.

There is a current debate in the literature regarding the optimal dosage of repetitive task training (such as mCIMT) during the acute stages of stroke. A systematic review by Nijland, Kwakkel, Bakers, and van Wegen (2011) suggests that low intensity CIMT (less than 3 hours of shaping/day and less than 90% restraint of the non-involved UE) compared to high intensity CIMT (> 3 hours of shaping/day in combination with restraint of the non-involved UE for 90% of waking hours) may be more beneficial during the acute and sub-acute stages of stroke.  The acute and sub-acute stage was defined as within the first 10 weeks after a stroke.

Explaining Plasticity after stroke (EXPLICIT) is a study designed to explore the underlying mechanisms of UE recovery following stroke during the acute stages. This multi-center trial is currently underway with the aim of determining the effectiveness of a form of early applied mCIMT on stroke recovery mechanisms.

Continue —>  New Acronyms in the Neurorehabilitation Literature; What Do They Mean? – SaeboSaebo

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[ARTICLE] Constraint-induced movement therapy for upper extremities in people with stroke.

Abstract

BACKGROUND:In people who have had a stroke, upper limb paresis affects many activities of daily life. Reducing disability is therefore a major aim of rehabilitative interventions. Despite preserving or recovering movement ability after stroke, sometimes people do not fully realise this ability in their everyday activities. Constraint-induced movement therapy (CIMT) is an approach to stroke rehabilitation that involves the forced use and massed practice of the affected arm by restraining the unaffected arm. This has been proposed as a useful tool for recovering abilities in everyday activities.

OBJECTIVES:To assess the efficacy of CIMT, modified CIMT (mCIMT), or forced use (FU) for arm management in people with hemiparesis after stroke.

SEARCH METHODS:We searched the Cochrane Stroke Group trials register (last searched June 2015), the Cochrane Central Register of Controlled Trials (CENTRAL; The Cochrane Library Issue 1, 2015), MEDLINE (1966 to January 2015), EMBASE (1980 to January 2015), CINAHL (1982 to January 2015), and the Physiotherapy Evidence Database (PEDro; January 2015).

SELECTION CRITERIA:Randomised control trials (RCTs) and quasi-RCTs comparing CIMT, mCIMT or FU with other rehabilitative techniques, or none.

DATA COLLECTION AND ANALYSIS:One author identified trials from the results of the electronic searches according to the inclusion and exclusion criteria, three review authors independently assessed methodological quality and risk of bias, and extracted data. The primary outcome was disability.

MAIN RESULTS:We included 42 studies involving 1453 participants. The trials included participants who had some residual motor power of the paretic arm, the potential for further motor recovery and with limited pain or spasticity, but tended to use the limb little, if at all. The majority of studies were underpowered (median number of included participants was 29) and we cannot rule out small-trial bias. Eleven trials (344 participants) assessed disability immediately after the intervention, indicating a non-significant standard mean difference (SMD) 0.24 (95% confidence interval (CI) -0.05 to 0.52) favouring CIMT compared with conventional treatment. For the most frequently reported outcome, arm motor function (28 studies involving 858 participants), the SMD was 0.34 (95% CI 0.12 to 0.55) showing a significant effect (P value 0.004) in favour of CIMT. Three studies involving 125 participants explored disability after a few months of follow-up and found no significant difference, SMD -0.20 (95% CI -0.57 to 0.16) in favour of conventional treatment.

AUTHORS’ CONCLUSIONS:CIMT is a multi-faceted intervention where restriction of the less affected limb is accompanied by increased exercise tailored to the person’s capacity. We found that CIMT was associated with limited improvements in motor impairment and motor function, but that these benefits did not convincingly reduce disability. This differs from the result of our previous meta-analysis where there was a suggestion that CIMT might be superior to traditional rehabilitation. Information about the long-term effects of CIMT is scarce. Further trials studying the relationship between participant characteristics and improved outcomes are required.

Source: Constraint-induced movement therapy for upper extremities in people with stroke. – PubMed – NCBI

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