Posts Tagged Neurofenix

[ARTICLE] Rehabilitation via HOMe Based gaming exercise for the Upper-limb post Stroke (RHOMBUS): protocol of an intervention feasibility trial – Full Text


Introduction Effective interventions to promote upper-limb recovery poststroke are characterised by intensive and repetitive movements. However, the repetitive nature of practice may adversely impact on adherence. Therefore, the development of rehabilitation devices that can be used safely and easily at home, and are motivating, enjoyable and affordable is essential to the health and well-being of stroke survivors.

The Neurofenix platform is a non-immersive virtual reality device for poststroke upper-limb rehabilitation. The platform uses a hand controller (a NeuroBall) or arm bands (NeuroBands) that facilitate upper-limb exercise via games displayed on a tablet. The Rehabilitation via HOMe Based gaming exercise for the Upper-limb post Stroke trial aims to determine the safety, feasibility and acceptability of the Neurofenix platform for home-based rehabilitation of the upper-limb poststroke.


Methods and analysis Thirty people poststroke will be provided with a Neurofenix platform, consisting of a NeuroBall or NeuroBands (dependent on impairment level), seven specially designed games, a tablet and handbook to independently exercise their upper limb for 7 weeks. Training commences with a home visit from a research therapist to teach the participant how to safely use the device. Outcomes assessed at baseline and 8 weeks and 12 weeks are gross level of disability, pain, objectively measured arm function and impairment, self-reported arm function, passive range of movement, spasticity, fatigue, participation, quality of life (QOL) and health service use. A parallel process evaluation will assess feasibility, acceptability and safety of the intervention through assessment of fidelity to the intervention measured objectively through the Neurofenix platform, a postintervention questionnaire and semistructured interviews exploring participants’ experiences of the intervention. The feasibility of conducting an economic evaluation will be determined by collecting data on QOL and resource use.

Strengths and limitations of this study

  • The Rehabilitation via HOMe Based gaming exercise for the Upper-limb post Stroke trial will investigate the feasibility, acceptability and safety of a novel gaming platform (the Neurofenix platform) at home for upper-limb exercise after stroke.

  • Upper-limb activity data will be objectively measured by the device. Assessment outcome measures include objective (assessed blind to timepoint) and self-reported measures.

  • To be maximally inclusive, stroke survivors with moderate to severe arm impairment will be included in the study.

  • The feasibility of conducting an economic evaluation will be determined by collected data on quality of life and resource use.

  • This is a home-based intervention study; thus, participants and researchers collecting the data will not be blinded.


Stroke is the leading cause of severe disability worldwide with approximately 17 million new strokes each year.1 2 The UK has 1.2 million stroke survivors with 110 000 first-time strokes occurring each year resulting in an estimated societal cost of £26 billion per year.1 2 Following stroke, 85% of people initially experience upper-limb weakness, and of those with minimal movement on hospital admission, only 11%–14% regain full function of their arm.2–4 This loss in upper-limb function results in increased dependence and decreased quality of life (QOL).5 Reduced upper-limb function has been identified as a strong predictor of lowered psychological well-being poststroke.5 6 Innovation and investigation of effective treatments for arm recovery has been identified as a priority for stroke research.7

Evidence indicates the most effective interventions to improve upper-limb function are characterised by high intensity and repetitive practice.8 A higher intensity and frequency of upper-limb stroke rehabilitation is associated with improved QOL,9 motor function and ability to perform activities of daily life10 and is cost-effective.11 The UK quality standard for stroke advises 45 min of each relevant therapy for a minimum of 5 days a week.11 However, a 2015 UK national stroke audit showed on average most hospitals are unable to meet this quality standard.12 Specifically, time spent retraining the upper limb is very low, with an average of 32 repetitions per rehabilitation session.13 14 As such, there is a growing emphasis on the stroke survivor exercising independently without the presence of a therapist. However, adherence to home exercise is known to be poor.15 16 A perceived lack of support and feedback along with boredom with exercises are the most frequently cited factors associated with poor compliance.17 18

Virtual reality (VR)-based activities have been suggested as an intervention to improve upper-limb recovery by providing motivating environments or gameplay to facilitate rehabilitation.19 This digital health solution helps address boredom and compliance problems, can facilitate increased time in therapy and may not be reliant on therapist contact time.19 20 In addition, the ability of VR activities to provide feedback may enhance motor learning.21 22 Visual feedback via an on-screen character (avatar) can activate mirror neurones, which may aid recovery from stroke.23 24

VR can be considered in terms of the level of immersion provided, that is, the degree the user feels present in the virtual world due to the technical aspects of the VR environment. Immersive systems can generate life-scaled, three-dimensional images, with surround sound auditory and sensory feedback such as vibration, and pressure,25 whereas non-immersive systems involve two-dimensional images typically viewed on a screen with interaction being via controller-based systems (such as computer keyboards, joysticks, balance boards and handheld devices) or via camera-based tracking systems.26 Non-immersive systems are more commonly used for rehabilitation as they have smaller space requirements, cost less and have fewer side effects (eg, motion sickness).27

The Neurofenix platform is a non-immersive device designed to enable and encourage stroke survivors to independently exercise their upper limb with minimal therapist input. The platform was developed by Neurofenix, a bioengineering enterprise (, along with stroke survivors and neurological physiotherapists. The platform consists of a hand controller or armbands, seven specially designed games, a tablet and an instruction handbook.[…]

Continue —> Rehabilitation via HOMe Based gaming exercise for the Upper-limb post Stroke (RHOMBUS): protocol of an intervention feasibility trial | BMJ Open

Figure 1. Rehabilitation via HOMe Based gaming exercise for the Upper-limb post Stroke (RHOMBUS) trial design.

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[WEB SITE] Neurofenix – Transforming stroke care delivery

Arm & hand exercising made fun

The key to recover arm and hand use after a stroke is exercising every day.
However, this can be painfully boring and in fact many survivors stop doing it. This is also because of lack of motivation and support.

Our NeuroBall allows stroke survivors to do hundreds of repetitions daily without even realizing it. That’s because the NeuroBall is a controller used by the impaired hand to play videogames, making exercising fun. But what makes it really special is the fact that we designed it together with stroke survivors, their families, therapists and physicians, so it takes into account your real needs.

Stay tuned about the NeuroBall release in late 2018!

STAY INFORMED Or tell a friend who might be interested

The Neuroball and some games

Progress tracking

Improvements can be monitored
easily, so that every small success can
be celebrated with the loved ones.

Easy to set up

It can be used independently at home
or with little support, lessening
dependance on others.

Social, fun and engaging

It’s for everyone! Survivors can play
with other survivors, their families
and friends.


Are you a therapist?

Neurofenix’s NeuroBall is a great addition to your toolkit. It’s fun and engaging, so you can enhance training in-between sessions to amplify your hands-on therapy.


• One-size-fits-all design, suitable for mild to severe impairments
• Extremely motivating, ideal to train in-between sessions
• Possibility to track progress remotely

ENROLL TO TRY IT FOR FREE Or tell a friend who might be interested

NeuroBall’s main exercises

Wrist Ulnar Radiation DeviationWrist Ulnar Radial Deviation
Forearm Pronation and SupinationForearm Pronation and Supination
Wrist Flexion and ExtensionWrist Flexion and Extension
Reaching movementReaching movement
Grasp and ReleaseGrasp and Release
Elbow and shoulder trainingElbow and shoulder training

Are you a relative, a friend or a carer?

After leaving the hospital stroke survivors and their families are often given little or no guidance on what to do.

Our NeuroBall gives families, friends and carers a clear way to maximise

Family and friends

• Get clear instructions on type and duration of exercises your
oved one’s potential to get better:

• Empower your loved ones to self-manage their training
• Keep up motivation with daily rewards and by measuring improvement

ENROLL TO TRY IT FOR FREE Or tell a friend who might be interested

Who else can benefit from the NeuroBall?

Our NeuroBall can be beneficial to anyone with an impaired hand and/or arm who needs to get better, including individuals with: traumatic brain injury, multiple sclerosis, spinal cord injury, cerebral palsy, osteoarthritis and hand injuries.

STAY INFORMED Or tell a friend who might be interested

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