Posts Tagged recovery

[Abstract] An interactive and innovative application for hand rehabilitation through virtual reality

Physiotherapy has been very monotonous for patients and they tend to lose interest and motivation in exercising. Introducing games with short term goals in the field of rehabilitation is the best alternative, to maintain patients’ motivation. Our research focuses on gamification of hand rehabilitation exercises to engage patients’ wholly in rehab and to maintain their compliance to repeated exercising, for a speedy recovery from hand injuries (wrist, elbow and fingers). This is achieved by integrating leap motion sensor with unity game development engine. Exercises (as gestures) are recognised and validated by leap motion sensor. Game application for exercises is developed using unity. Gamification alternative has been implemented by very few in the globe and it has been taken as a challenge in our research. We could successfully design and build an engine which would be interactive and real-time, providing platform for rehabilitation. We have tested the same with patients and received positive feedbacks. We have enabled the user to know the score through GUI.

 

via An interactive and innovative application for hand rehabilitation through virtual reality: International Journal of Advanced Intelligence Paradigms: Vol 15, No 3

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[Abstract] What is the potential of virtual reality for post-stroke sensorimotor rehabilitation?

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via What is the potential of virtual reality for post-stroke sensorimotor rehabilitation?: Expert Review of Neurotherapeutics: Vol 0, No 0

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[BLOG POST] Hope Clark on “My new normal” following her brain injury – Jumbledbrain

Today I want to introduce you to Hope Clark. She is a talented writer, who has written about learning disabilities and has written a couple of articles for some local newspapers. Plus there are plenty of articles written about her. These articles can be found archived at the National Library in Ottawa.

Since her brain injury she wrote few pieces as part of her therapy. However, she has now decided to share them publicly and hopes (no pun intended) that they will help others.

“I am from SW Ontario, Canada.  My past like is filled with Management positions, Event Planning, Fundraising and Marketing with a side of Communications. Writing for me is something I find very cathartic. I acquired my TBI in March of 2018 and have been trying to reinvent myself ever since. I am not sure what I am going to do when I grow up, but if I can help someone with my writing then I feel I have done my job.” – Hope Clark aka HM Lemon

This is an extract of one of her articles. You can read the full version of My new normal which she has published on Facebook here.


As the thick veil of trauma has slowly been dissolving over the past year, nine months, 5 days (you get the gist) my life has been interesting to say the least. I have been the most alone I have ever been even though, unlike before, I have a loving husband and two beautiful children. Don’t get me wrong, I have been treated with great empathy, compassion and caring.

My road to recovery has been met with other trauma victims, doctor’s, specialists, treatment providers: I am never alone, yet, I am the most alone I have ever been.

Living with a traumatic brain injury and trauma really does lend itself to the saying, ‘if you have never experienced it, you just won’t understand.’ You try to be like your old self, or your normal and no matter what happens…something you’ve never experienced before rears its ugly head. It is true what they say, ‘Don’t take things for granted because you never know what could happen”, is taken to the extreme!

I can’t drop my kids off at school because the commotion of the people, vehicles, movement, noise – it makes me so sick to the point my brain feels like it will explode. My ‘level of tolerance’ as the treatment providers call it is about 2 hours. When I meet a friend for a lunch, little do they know that I must sleep for 2 – 3 hours afterwards just to recover. This coming from a woman who would get up at 6 am to workout before getting the kids up at 7 am and then not stopping until around midnight. This schedule repeated day after day. Some other wonderful side effects of an MVA are, yet not limited to, screen time (computer and television) gives me headaches; my wonderfully intelligent brain now struggles with sentence structure, word recall and spelling and even executive functioning. My love of music has been put on mute and my awesome dance parties with the kids have been put on hold. I keep hearing the term, ‘new normal’ – and that is very difficult to wrap my head around. Living 44 years is a long time. You acquire certain traits, characteristics and now to be told that that isn’t you anymore is a struggle. At the same time, I am being told that I am extremely high functioning. What does that even mean!? Lol! Until recently I didn’t understand this until my OT said something of brilliance.
Living with a traumatic brain injury and trauma really does lend itself to the saying, ‘if you have never experienced it, you just won’t understand.’

You try to be like your old self, or your normal and no matter what happens…something you’ve never experienced before rears its ugly head.

It is true what they say, ‘Don’t take things for granted because you never know what could happen”, is taken to the extreme!

I can’t drop my kids off at school because the commotion of the people, vehicles, movement, noise – it makes me so sick to the point my brain feels like it will explode. My ‘level of tolerance’ as the treatment providers call it is about 2 hours. When I meet a friend for a lunch, little do they know that I must sleep for 2 – 3 hours afterwards just to recover. This coming from a woman who would get up at 6 am to workout before getting the kids up at 7 am and then not stopping until around midnight. This schedule repeated day after day. Some other wonderful side effects of an MVA are, yet not limited to, screen time (computer and television) gives me headaches; my wonderfully intelligent brain now struggles with sentence structure, word recall and spelling and even executive functioning. My love of music has been put on mute and my awesome dance parties with the kids have been put on hold. I keep hearing the term, ‘new normal’ – and that is very difficult to wrap my head around. Living 44 years is a long time. You acquire certain traits, characteristics and now to be told that that isn’t you anymore is a struggle. At the same time, I am being told that I am extremely high functioning. What does that even mean!? Lol! Until recently I didn’t understand this until my OT said something of brilliance.

‘We can go our whole lives living a certain way and one little bonk to the brain and yep, you have to relearn your whole way of life and living.’ Crazy enough it made me feel a bit better. I understood what people were trying to tell me about my ‘New Normal.’ 

Living with a TBI, (traumatic brain injury) is your brain telling you that you just can’t!

What does that mean exactly? When my level of tolerance has been met my brain begins to feel like it’s on fire. You are most likely saying once again, what does that mean? Well, it’s like when you begin to get the flu and your head feels like you’re starting get a fever, that is what my head feels like – yet, without the flu. I begin to get foggy. My concentration levels start to fade. My ability to understand let alone comprehend what the person I am with is saying it to is slim to none and I am unable to make eye contact with whom I am with because my brain is too busy trying to keep up. Oh yes, comprehension has left the building everyone and thank gawd for spell check. This coming from the woman who has been published, interviewed for television, print and radio more times than I can count. On Mother’s Day 2019, I dropped to the floor in front of my family. Out cold I was, and an ambulance had to be called. I spent the day in the ER. Just before I was released the doctor came and tried to explain what was going on. We had a conversation and when she walked away, my mom said – honey, you did NOT understand a word she was saying. I was mortified. This isn’t the only time this has happened, and I was oddly humbled by the experience. The great news is that my memory is completely shot so the likelihood of me remembering these highly embarrassing moments are unlikely. 

Memory: I did have one almost 2 years ago. I had a great memory and my jobs reflected by ability to hold large amounts of information. Now, I forget to turn off the stove or close the fridge. I lose my thought(s) in mid-sentence, knowing there was something there and at the same time not having a clue what I was saying, doing, or what the topic was. Grabbing and putting the wrong lid on something is day after day. I forget my children’s names. In my defence, it is mostly when I am upset of my tolerance levels have been met and asking them to go brush their teeth or get ready for bed. My daughter just looks at me as says, ‘Mom, why are you telling me to go to the kitchen!? Don’t you want me to go to the bathroom, cause we’re already in the kitchen?’ My response, ‘Om-goodness, you understood what I am trying to say so please just go,’ Lol.

Honestly, looking at your brain injury with a positive outlook is the only way to be. The truth is that you can not control the future, only your present. You have no idea when and if you will be 100% and that is okay. It is okay because you can begin to reinvent yourself and how many people really get the chance to do that? Every step forward is a victory. Each and every day you can manage the pain, headaches and nausea is a bonus! You just push forward with whatever you have left. Be thankful for every moment you get to spend with your children and jump for joy that they were not in the car with you. And, even though you miss experiences and moments with your children – you get to be there with them in the small moments: putting them to bed, helping them brush their teeth, making dinner because all moments and experiences are important. You cherish and laugh out loud when your 6-yr old tells you to piss off; and, when your 8-yr-old daughter wants to just sit and cuddle with you for hours. And, this is where I leave you 1 year, 9 months, 15 days,…for now.

Other articles you may like:

Does this sound familiar to you? What has it been like having to accept what is your new normal following a brain injury?

via Guest post: Hope Clark on “My new normal” following her brain injury. | Jumbledbrain

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[VIDEO] Recovery from Brain Injury Occurs for the Rest of a Person’s Life – YouTube

The human brain is a wonderful organ with amazing flexibility. Learn more about recovery.

via Recovery from Brain Injury Occurs for the Rest of a Person’s Life – YouTube

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[BLOG] PROMOTING A BRAIN HEALING LIFESTYLE

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[Brochure] Understanding TBI Part 4: The impact of a recent TBI on family members and what they can do to help with recovery

How does brain injury affect family members?

For most family members, life is not the same after TBI. We want you to know that you are not alone in what you are feeling. While everyone’s situation is a bit different, there are some common problems that many family members experience such as less time for yourself, financial difficulties, role changes of family members, problems with communication, and lack of support from other family members and friends. These are just some of the problems that family members may face after injury. Sometimes these problems can seem too much and you may become overwhelmed, not seeing any way out. Family members have commonly reported feeling sad, anxious, angry, guilty, and frustrated.[…]

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[ARTICLE] Recovery of upper limb function is greatest early after stroke but does continue to improve during the chronic phase: a two-year, observational study – Full Text

Abstract

Objectives

Investigate upper limb (UL) capacity and performance from <14-days to 24-months post-stroke.

Design

Longitudinal study of participants with acute stroke, assessed ≤14-days, 6-weeks, 3-, 6-, 12-, 18-, and 24-months post-stroke.

Setting

Two acute stroke units.

Main outcome measures: Examination of UL capacity using Chedoke McMaster Stroke Assessment (combined arm and hand scores, 0 to 14), performance using Motor Activity Log (amount of movement and quality of movement, scored 0 to 5), and grip strength (kg) using Jamar dynamometer. Random effects regression models were performed to explore the change in outcomes at each time point. Routine clinical imaging was used to describe stroke location as cortical, subcortical or mixed.

Results

Thirty-four participants were enrolled: median age 67.7 years (IQR 60.7 to 76.2), NIHSS 11.5 (IQR 8.5 to 16), female n = 10 (36%). The monthly rate of change for all measures was consistently greatest in the 6-weeks post-baseline. On average, significant improvements were observed to 12- months in amount of use (median improvement 1.81, 95% CI 1.35 to 2.27) and strength (median improvement 8.29, 95% CI 5.90 to 10.67); while motor capacity (median improvement 4.70, 95% CI 3.8 to 5.6) and quality of movement (median improvement 1.83, 95% CI 1.37 to 2.3) improved to 18-months post-stroke. Some individuals were still demonstrating gains at 24-months post-stroke within each stroke location group.

Conclusion

This study highlights that the greatest rate of improvement of UL capacity and performance occurs early post-stroke. At the group level, improvements were evident at 12- to 18-months post-stroke, but at the individual level improvements were observed at 24-months.

Introduction

Up to 70% of individuals experience difficulties using their upper limb (UL, arm and hand) to perform meaningful activities after stroke [1]. There is an assumption that when a stroke survivor demonstrates a change in activity, it is underpinned by an improvement in their capacity (i.e., what a person can do in the clinical environment) and performance (i.e., does a person actually use their UL in real world environments outside of the clinic) [2]. However, UL recovery post-stroke is unlikely to be this simplistic [3]. Understanding how capacity and performance change over years post-stroke might help to identify which patients to target and when during their recovery.

Previous research has noted distinct recovery profiles during inpatient [4][5] and outpatient [6] rehabilitation. Firstly, survivors may demonstrate improvements in both capacity and performance after stroke. Secondly, survivors may demonstrate an improvement in capacity but not performance. Lastly, survivors may demonstrate little or no change in both capacity and performance. An improvement in performance but not capacity has not been documented in the literature. Combined, these profiles support our rationale that UL capacity and performance are interrelated, yet are different constructs that must be measured separately.

Stroke recovery is a long-term goal. It is important to complete observational studies that track recovery to establish whether there is a discrepancy between capacity and performance in the long-term. To date, longitudinal tracking of recovery has largely lacked investigation of natural recovery from an acute time point post-stroke (first 7- to 14-days), long-term follow up of patients beyond 3- to 6-months post-stroke, and characterisation of stroke variables such as lesion type and location that may modify or interact with observed recovery profiles [7].

In this exploratory study our objectives were to determine 1) whether UL capacity and performance improve over the first 24-months after stroke; and 2) if there is a window of greatest improvement in UL capacity and performance. This information is important to develop an understanding of the longterm timecourse of recovery after stroke to support evidence-based clinical practice guidelines to inform upper limb rehabilitation services.

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Continue —-> Recovery of upper limb function is greatest early after stroke but does continue to improve during the chronic phase: a two-year, observational study – ScienceDirect

Fig. 2

Fig. 2. Upper limb motor capacity (Chedoke), performance (quality of movement & amount of use), and grip strength over 24-months post-stroke (n = 28)

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[ARTICLE] What the Proportional Recovery Rule Is (and Is Not): Methodological and Statistical Considerations – Full Text

In 2008, it was proposed that the magnitude of recovery from nonsevere upper limb motor impairment over the first 3 to 6 months after stroke, measured with the Fugl-Meyer Assessment (FMA), is approximately 0.7 times the initial impairment (“proportional recovery”). In contrast to patients with nonsevere hemiparesis, about 30% of patients with an initial severe paresis do not show such recovery (“nonrecoverers”). Hence it was suggested that the proportional recovery rule (PRR) was a manifestation of a spontaneous mechanism that is present in all patients with mild-to-moderate paresis but only in some with severe paresis. Since the introduction of the PRR, it has subsequently been applied to other motor and nonmotor impairments. This more general investigation of the PRR has led to inconsistencies in its formulation and application, making it difficult to draw conclusions across studies and precipitating some cogent criticism. Here, we conduct a detailed comparison of the different studies reporting proportional recovery and, where appropriate, critique statistical methodology. On balance, we conclude that existing data in aggregate are largely consistent with the PRR as a population-level model for upper limb motor recovery; recent reports of its demise are exaggerated, as these excessively focus on the less conclusive issue of individual subject-level predictions. Moving forward, we suggest that methodological caution and new analytical approaches will be needed to confirm (or refute) a systematic character to spontaneous recovery from motor and other poststroke impairments, which can be captured by a mathematical rule either at the population or at the subject level.

It has been appreciated since Hippocrates that the strongest predictor of final motor impairment after stroke is initial impairment (Aphorisms of Hippocrates, Section 2: 42). A prominent poststroke motor impairment in humans is the intrusion of unwanted synergies, with synergy referring to a systematic pattern of either joint co-articulation or muscle co-activation. The Fugl-Meyer Assessment (FMA) was explicitly developed to track progression of recovery from such synergies. A seminal study tracking the recovery of patients using the upper extremity subscale of the Fugl-Meyer Assessment (FMA-UE) demonstrated that more severely affected patients saw greater recovery in this outcome, on average, than more mildly affected patients in the immediate poststroke recovery period1; however, the average final score of the FMA-UE among the severly affected still trailed behind the mildly affected. The authors of this study stated, “The most dramatic recovery in motor function occurred over the first 30 days, regardless of the initial severity of the stroke.” On the basis of this study and other considerations, Krakauer et al2 sought to investigate the nature of this FMA-UE change early after stroke; work that led to the formulation of the proportional recovery rule (PRR).2 The PRR states that patients recover approximately 70% of their maximal potential reduction in impairment as measured by the FMA.2

Since it was introduced, the PRR has been applied in a broad range of studies that involve recovery from stroke, both for FMA-UE and for other outcomes. Claims related to the PRR have been made for upper and lower limb impairment measured by the FMA,310 aphasia measured with the Western Aphasia Battery (WAB),11 the resting motor threshold (RMT) of the extensor carpi radialis,6 and visuospatial neglect measured with the Letter Cancellation Test (LCT),12 among others. Applications of the PRR typically distinguish between two distinct subgroups of patients, referred to as “recoverers” and “nonrecoverers”: the former subgroup is composed of patients who recover a significant amount of lost function, and the latter is composed of those who do not. The PRR is thought to usefully characterize the recovery process among recoverers only. Although the methods by which the PRR was applied and evaluated have differed substantially across publications, many authors have argued that their findings are evidence for a PRR that accurately describes an underlying biological process that arises across neurolocical domains. Recently, however, the PRR has been the subject of criticism related to the validity of the statistical methods underlying its implementation and to the degree to which data are consistent with claims in support of the PRR.13,14 Much of the critique on the PRR articulated by these articles was focused on specific statements associated with the PRR followed by a general dismissal of all findings.

Our goal in this work is to provide a critical reexamination of the literature pertaining to the PRR. We focus first on the interpretation and implementation of PRR as a statistical model, and on data-driven concerns about the use of the PRR in studies of recovery. We then reexamine data reported in the literature and the extent to which past studies provide evidence for the PRR with these considerations in mind. Our hope is that this will serve as an instructive overview of issues that can arise in the application of the PRR to studies of recovery, aiming to improve future investigations into the PRR. Although our primary purpose is not to provide direct response to recent critiques,13,14 we are mindful of the concerns raised and address these directly in the Discussion section.

The breadth of work on the PRR introduces a commensurate range of methodological concerns one might consider. We attempt to be complete in our discussion but prefer to focus on overarching concerns regarding the statistical validity of the PRR instead of point-by-point inspections of the existing literature. Two themes we will revisit while pursuing the main goals of this paper are the identification of recoverers and the distinction between describing biological mechanisms and making patient-level predictions. The manner in which nonrecoverers are identified is a point of legitimate concern, as some statistical approaches can artifactually create evidence for the PRR. The PRR was originally intended to describe biological mechanisms at the population level, although implicitly it is expected that the PRR may be useful for predicting recovery of individual patients. Both of these are related to recent concerns regarding the PRR.

The next section provides an overview of the statistical formulation of the PRR and introduces three simulated datasets to illustrate scenarios over which the PRR shows varying degrees of validity. Subsequent sections conduct a selective review of the literature, reevaluating specific articles in the light of the three scenarios, comment on recent criticisms of the PRR, and end with our current view on the veracity of the PRR.

[…]

 

Continue —>  What the Proportional Recovery Rule Is (and Is Not): Methodological and Statistical Considerations – Robinson Kundert, Jeff Goldsmith, Janne M. Veerbeek, John W. Krakauer, Andreas R. Luft,

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[Abstract] Medical Mobile Applications for Stroke Survivors and Caregivers

Abstract

Background

Recent studies estimate nearly half of the US population can access mobile medical applications (apps) on their smartphones. The are no systematic data available on apps focused on stroke survivors/caregivers.

Objective

To identify apps (a) designed for stroke survivors/caregivers, (b) dealing with a modifiable stroke risk factor (SRF), or (c) were developed for other purposes but could potentially be used by stroke survivors/caregivers.

Methods

A systematic review of the medical apps in the US Apple iTunes store was conducted between August 2013 and January 2016 using 18 predefined inclusion/exclusion criteria. SRFs considered were: diabetes, hypertension, smoking, obesity, atrial fibrillation, and dyslipidemia.

Results

Out of 30,132 medical apps available, 843 (2.7%) eligible apps were identified. Of these apps, (n = 74, 8.7%) apps were specifically designed for stroke survivors/caregivers use and provided the following services: language/speech therapy (n = 28, 37%), communication with aphasic patients (n = 19, 25%), stroke risk calculation (n = 11, 14%), assistance in spotting an acute stroke (n = 8, 10%), detection of atrial fibrillation (n = 3, 4%), direction to nearby emergency room (n = 3, 4%), physical rehabilitation (n = 3, 4%), direction to the nearest certified stroke center (n = 1, < 2%), and visual attention therapy (n = 1, <2%). 769 apps identified that were developed for purposes other than stroke. Of these, the majority (n = 526, 68%) addressed SRFs.

Conclusions

Over 70 medical apps exist to specifically support stroke survivors/caregivers and primarily targeted language and communication difficulties. Apps encompassing most stroke survivor/caregiver needs could be developed and tested to ensure the issues faced by these populations are being adequately addressed.

via Medical Mobile Applications for Stroke Survivors and Caregivers – ScienceDirect

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[Abstract] Pharmacological interventions and rehabilitation approach for enhancing brain self-repair and stroke recovery

Abstract

Neuroplasticity is a natural process occurring in the brain for entire life. Stroke is the leading cause of long term disability and huge medical and financial problem throughout the world. Research conducted over the past decade focused mainly on neuroprotection in the acute phase of stroke while very little studies targets chronic stage. Recovery after stroke depends on the ability of our brain to reestablish structural and functional organization of neurovascular networks. Combining adjuvant therapies and drugs may enhance the repair processes and restore impaired brain functions. Currently, there are some drugs and rehabilitative strategies that can facilitate brain repair and improve clinical effect even years after stroke onset. Moreover, some of compounds such as citicoline, fluoxetine, niacin, levodopa etc. are already in clinical use or are being trial in clinical issues. Many studies testing also cell therapies, in our review we will focused on studies where cells have been implemented at the early stage of stroke. Next, we discuss pharmaceutical interventions. In this section selected methods of cognitive, behavioral and physical rehabilitation as well as adjuvant interventions for neuroprotection including non invasive brain stimulation and extremely low frequency electromagnetic field. The modern rehabilitation represents new model of physical interventions with limited therapeutic window up to six months after stroke. However, last studies suggest, that time window for stroke recovery is much longer than previous thought. This review attempts to present the progress in neuroprotective strategies, both pharmacological and non-pharmacological that can stimulate the endogenous neuroplasticity in post stroke patients.

 

via Pharmacological interventions and rehabilitation approach for enhancing brain self-repair and stroke recovery | Bentham Science

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