Posts Tagged seizures

[WEB SITE] New epilepsy warning device could save thousands of lives — ScienceDaily

Nightwatch bracelet on the arm of a young epilepsy patient.
Credit: LivAssured

A new high-tech bracelet, developed by scientists from the Netherlands detects 85 percent of all severe night-time epilepsy seizures. That is a much better score than any other technology currently available. The researchers involved think that this bracelet, called Nightwatch, can reduce the worldwide number of unexpected night-time fatalities in epilepsy patients. They published the results of a prospective trial in the scientific journal Neurology.

SUDEP, sudden unexpected death in epilepsy, is a major cause of mortality in epilepsy patients. People with an intellectual disability and severe therapy resistant epilepsy, may even have a 20% lifetime risk of dying from epilepsy. Although there are several techniques for monitoring patients at night, many attacks are still being missed.

Consortium researchers have therefore developed a bracelet that recognizes two essential characteristics of severe attacks: an abnormally fast heartbeat, and rhythmic jolting movements. In such cases, the bracelet will send a wireless alert to carers or nurses.

The research team prospectively tested the bracelet, known as Nightwatch, in 28 intellectually handicapped epilepsy patients over an average of 65 nights per patient. The bracelet was restricted to sounding an alarm in the event of a severe seizure. The patients were also filmed to check if there were any false alarms or attacks that the Nightwatch might have missed. This comparison shows that the bracelet detected 85 percent of all serious attacks and 96% of the most severe ones (tonic-clonic seizures), which is a particularly high score.

For the sake of comparison, the current detection standard, a bed sensor that reacts to vibrations due to rhythmic jerks, was tested at the same time. This signalled only 21% of serious attacks. On average, the bed sensor therefore remained unduly silent once every 4 nights per patient. The Nightwatch, on the other hand, only missed a serious attack per patient once every 25 nights on average. Furthermore, the patients did not experience much discomfort from the bracelet and the care staff were also positive about the use of the bracelet.

These results show that the bracelet works well, says neurologist and research leader Prof. Dr. Johan Arends. The Nightwatch can now be widely used among adults, both in institutions and at home. Arends expects that this may reduce the number of cases of SUDEP by two-thirds, although this also depends on how quickly and adequately care providers or informal carers respond to the alerts. If applied globally, it can save thousands of lives.

Watch the video here:

Story Source:

Materials provided by Eindhoven University of TechnologyNote: Content may be edited for style and length.

Journal Reference:

  1. Johan Arends, Roland D. Thijs, Thea Gutter, Constantin Ungureanu, Pierre Cluitmans, Johannes Van Dijk, Judith van Andel, Francis Tan, Al de Weerd, Ben Vledder, Wytske Hofstra, Richard Lazeron, Ghislaine van Thiel, Kit C.B. Roes, Frans Leijten. Multimodal nocturnal seizure detection in a residential care settingNeurology, 2018; 10.1212/WNL.0000000000006545 DOI: 10.1212/WNL.0000000000006545

via New epilepsy warning device could save thousands of lives — ScienceDaily

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[WEB SITE] New Epilepsy Bracelet Could Save Thousands of Lives

High-Tech “Nightwatch” is Capable of Detecting 85 Percent of Severe Night-Time Epileptic Seizures

Scientists in the Netherlands are optimistic that their new device will reduce the number of sudden unexpected death in epilepsy (SUDEP) patients worldwide. Currently, for people with an intellectual disability and severe treatment-resistant epilepsy, the outlook is poor, with a possible 20 percent lifetime risk of dying from epilepsy. While several techniques exist for monitoring patients at night, many seizures are still being missed.

With this in mind, a consortium of researchers (from Kempenhaeghe epilepsy centre, Eindhoven University of Technology, the Foundation for Epilepsy Institutions in the Netherlands (SEIN), UMC Utrecht, the Epilepsy Fund, patient representatives, and LivAssured) developed Nightwatch, a bracelet that recognizes unusually fast heartbeat and rhythmic jolting movements, two critical characteristics of severe attacks. When these occur, the device sends a wireless alert to caregivers or nurses.

In a test among 28 intellectually handicapped patients with epilepsy, over an average of 65 nights, Nightwatch detected 85 percent of all serious attacks and 96 percent of the most severe ones (tonic-clonic seizures). In comparison, a bed sensor, which is the current detection standard, sounded the alarm for only 21 percent of serious attacks. While the bed sensor was silent once every four nights per patient, the Nightwatch only missed a serious attack once every 25 nights, on average.

Prof. Dr. Johan Arends, neurologist and research leader, expects that the bracelet may reduce the number of SUDEP cases by two-thirds, although this also depends on the speed and efficiency with which caregivers respond to the alerts.

Source:, October 29, 2018


via New Epilepsy Bracelet Could Save Thousands of Lives | Managed Care magazine

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[WEB SITE] Importance of Taking Medication on Schedule – Epilepsy Foundation

Taking Your Medication Regularly is Essential to Controlling Your Seizures

Taking seizure medications regularly, and as recommended by your doctor, is vitally important! It gives you the best chance to achieve the goals of epilepsy therapy: no seizures and no side effects. On the flip side, noncompliance with seizure medicines can have significant and possibly disastrous consequences.

Taking medicines regularly is easiest when you know about epilepsytreatment, and how to manage your seizures and medications. Managing medicines isn’t easy, but it certainly can be done! Think of it as a team approach involving your doctor, nurse, pharmacist, counselor, family and friends, and of course YOU. You are the captain of the team, because only you can decide if you are going to take the medicine. Only you can work together with the team to find ways to manage your meds best.

Here’s A Few Points About Why Adherence Is So Important.

  • You need to follow the doctor’s directions. If thos directions are confusing or complex, ask questions until you are sure you understand.
  • Seizure medicines must be taken each and every day as prescribed. If the right amount is not taken at the right time, the medicine may not be able to prevent seizures, or might cause unwanted side effects.
  • If the first medicine doesn’t work, others may be more successful.
  • Finding the right medicine at the right dose taken at the right time(s) of the day requires teamwork.
  • Any medication change recommended by the doctor is based on the assumption that the person has been taking the medicine the way it was intended. If this isn’t true, then the change may not work or may be the wrong thing to do!

Here are some thoughts by Joyce Cramer, a former president of the Epilepsy Therapy Project, that emphasizes the importance of medication compliance: The Titanic Impact of Medication Compliance on Epilepsy.

Learn More

via Importance of Taking Medication on Schedule | Epilepsy Foundation

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[WEB SITE] Driving and Epilepsy: Issues to Discuss With Your Patients

epilepsy, driving

Dr Sanchez is Assistant Professor and Dr Krumholz is Professor Emeritus, Department of Neurology, University of Maryland School of Medicine, Baltimore, MD.

Worldwide there are more than 65 million individuals with epilepsy.1In the US because driving an automobile is such an important aspect of our culture, driving restriction is an enormous problem for many of these individuals and their families. Indeed, surveys find individuals with epilepsy report driving as a major concern.2 Physicians and other medical providers play an important role educating and counseling people with seizures and their families regarding driving. Here, we provide some background and guidance regarding this issue.

Individuals with seizures are restricted from driving because of concerns that a seizure while driving might result in loss of control of the vehicle and a crash, potentially injuring the driver or others, and damaging property. Tragically, such crashes cause fatalities.3 Therefore every state in the US restricts some individuals with epilepsy from driving. Driving restrictions vary by state and are ultimately determined by the Department of Motor Vehicles (DMV).4 Physicians and other medical providers are involved to varying degrees throughout this process of driving regulation and restriction. They serve as advisers to patients, with a duty to inform patients regarding rules and regulations as well as consultants to state regulatory authorities.

To properly counsel patents, it is important that physicians and other medical providers are familiar with the rules governing driving for patients with seizure disorders. Our recommended approach to counseling patients with seizures and epilepsy regarding driving is illustrated in some of the following examples and discussion.

Case example
A 23-year-old woman presents to your office with new-onset seizures. She generally feels well, has no other relevant history, and her examination is normal. Brain MRI with and without contrast and EEG were performed and were normal.

Question: As the medical provider, how would you counsel this patient regarding driving after her first unprovoked seizure (a seizure not related to an acute precipitating cause)?

Answer: She should be informed that a seizure while driving could be dangerous and result in a motor vehicle crash. Since she has had a seizure, she is at risk for further seizures. Regulations exist in an effort to prevent injury, death, or property damage that might result if a seizure were to occur while driving. She should be informed to stop driving and that patients are required by law to report their seizures to the DMV in their state. In some states, physicians and other medical providers are also required to report (Table 1) that a patient has had a seizure.4 The DMV will determine when she may resume driving.

A seizure-free interval is typically necessary for the DMV to approve a person to drive after a first seizure, this too varies by state. The typically required seizure-free interval may be as short as three months to as long as one year.4 There may be positive or negative modifiers that shorten or lengthen the seizure-free interval (Table 2).5 Antiseizure medication (ASM) is not always prescribed after a first seizure; this is a variable that may be considered on a case by case basis.6

After reporting her seizures to the DMV, the patient and the medical provider are required to complete paperwork regarding the condition. A medical advisory board or similar type of state review will consider the case and make recommendations. Then a final decision regarding any driving restrictions will be made by the DMV. Decisions may be appealed by the patient.


via Driving and Epilepsy: Issues to Discuss With Your Patients | Neurology Times

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[BOOK] Seizures – Open access peer-reviewed Edited volume


Humberto Foyaca Sibat

Edited by Humberto Foyaca Sibat

Walter Sisulu University, Nelson Mandela Academic hospital

This book contains selected peer-reviewed articles that cover novel information on epileptic seizure and psychogenic non-epileptic seizures written by international researchers. In this book, we discuss self-reporting technologies for supporting epilepsy treatment. We also discuss about the diagnostic testing in epilepsy genetic clinical practice. Clinical aspects related to diagnosis in patients presenting psychogenic non-epileptic seizures vs. epileptic seizures and neurocysticercosis are discussed as well. We delivered novel aspects about the treatment for pseudoseizures. In another chapter, the authors estimated the prevalence of ischemic stroke in epileptic patients presenting subarachnoid neurocysticercosis and ischemic stroke frequency among HIV-positive patients, and finally other authors discuss autoimmune epilepsy, its new development, and its future directions. We are looking forward with confidence and pride to the remarkable role that this book will play for a new vision and mission.



SeizuresEdited by Humberto Foyaca Sibat
Published: May 2nd 2018

DOI: 10.5772/65137

ISBN: 978-1-78923-005-5

Print ISBN: 978-1-78923-004-8

Chapters Downloads

Open access peer-reviewed

1. Introductory Chapter: Seizures and Its Historical Background

By Humberto Foyaca-Sibat and Lourdes de Fátima Ibañez-Valdés


Open access peer-reviewed

2. Autoimmune Epilepsy: New Development and Future Directions

By Sandra Orozco-Suarez, Angélica Vega-Garcia, Iris Feria-Romero, Lourdes Arriaga-Pizano, Emmanuel Rodriguez-Chavez and Israel Grijalva


Open access peer-reviewed

3. Diagnostic Testing in Epilepsy Genetics Clinical Practice

By Birute Tumiene, Algirdas Utkus, Vaidutis Kučinskas, Aleš Maver and Borut Peterlin


Open access peer-reviewed

4. Self-Reporting Technologies for Supporting Epilepsy Treatment

By Jonathan Bidwell, Eliana Kovich, Cam Escoffery, Cherise Frazier and Elizabeth D. Mynatt


Open access peer-reviewed

5. Psychogenic Nonepileptic Seizures in Patients Living with Neurocysticercosis

By Lourdes de Fátima Ibañez-Valdés and Humberto Foyaca-Sibat


Open access peer-reviewed

6. Treatment and Diagnosis of Psychogenic Nonepileptic Seizures

By Cicek Hocaoglu


Open access peer-reviewed

7. Subarachnoid Cysticercosis and Ischaemic Stroke in Epileptic Patients

By Humberto Foyaca-Sibat and Lourdes de Fátima Ibañez-Valdés

via Seizures | IntechOpen

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[WEB SITE] List of Seizures (Convulsions) Medications (60 Compared) –

Medications for Seizures (Convulsions)

Other names: Absence Seizure; Complex Partial Seizure; Fits

About Seizures:  A seizure or convulsion can be a sudden, violent, uncontrollable contraction of a group of muscles. A seizure can also be more subtle, consisting of only a brief “loss of contact” or a few moments of what appears to be daydreaming.


Drugs Used to Treat Seizures

The following list of medications are in some way related to, or used in the treatment of this condition.[…]

For the list of medications, Visit Site —> List of Seizures (Convulsions) Medications (60 Compared) –

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[WEB SITE] This incredible smart band can help detect seizures when worn by people with epilepsy

Syndicate Post image

A seizure-detecting smart band could help people with epilepsy notify their caregivers in the event of an emergency.

Embrace, a smart band created by Empatica, uses advanced machine learning (AI) to monitor seizures, collecting physiological data from users to try to detect unusual events such as convulsive seizures.

The Embrace band is paired to a smartphone or iPod via Bluetooth connection and works in tandem with the Alert app, which sends SMS and phone call alerts to selected caregivers when a seizure is detected.

Embrace will send a command to the Alert app when it detects a seizure (Empatica)

Empatica CEO Matteo Lai said: “Embrace is a Medical Grade device in Europe and the only FDA-cleared seizure monitoring smart watch, which uses AI to monitor for the most dangerous kinds of seizures, known as ‘grand mal’ or ‘generalized tonic-clonic’ seizures, and send an alert to summon caregivers’ help.

“Embrace stands apart from any seizure detection system in that it measures multiple indicators of a seizure.

“Its unique property is its use of Electrodermal Activity, a signal used by stress researchers to quantify physiological changes related to sympathetic nervous system activity, also known as the ‘fight or flight’ response.”

When Embrace detects a seizure, it will send a command to the Alert app, which then sends an alert to the designated caregiver.

“Users can add caregivers who are notified in real time with a phone call and an SMS containing the wearer’s GPS location.

Lai said: “There is also another product that works with Embrace, a diary app called Mate, where the caregiver can monitor sleep and physical activity for patients wearing Embrace.

“The Mate app displays the seizures automatically detected by the Embrace and patients can also insert other, non-convulsive seizures that aren’t automatically detected.”

Embrace costs £177 (Empatica)

Morgan, a user of Embrace, said: “I purchased the Embrace mostly because my seizures have all happened during my sleep.

“I also purchased it so that I could regain a lot of the confidence that I lost once I was diagnosed with epilepsy.

“On November 6th 2016, I had a seizure(s) that lasted over 40 minutes. The Embrace detected the seizures and my emergency contacts were notified… I believe the Embrace saved my life. It helps give peace of mind to me, as well as my friends and family.

“Having the Embrace has also helped me regain the confidence to start being active again.”

Embrace costs 249 US dollars (£177), and is available from the Empatica website.


via This incredible smart band can help detect seizures when worn by people with epilepsy – Evening Express

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[Abstract] The management of epilepsy in children and adults.

The International League Against Epilepsy has recently published a new classification of epileptic seizures and epilepsies to reflect the major scientific advances in our understanding of the epilepsies since the last formal classification 28 years ago. The classification emphasises the importance of aetiology, which allows the optimisation of management. Antiepileptic drugs (AEDs) are the main approach to epilepsy treatment and achieve seizure freedom in about two-thirds of patients. More than 15 second generation AEDs have been introduced since the 1990s, expanding opportunities to tailor treatment for each patient. However, they have not substantially altered the overall seizure-free outcomes. Epilepsy surgery is the most effective treatment for drug-resistant focal epilepsy and should be considered as soon as appropriate trials of two AEDs have failed. The success of epilepsy surgery is influenced by different factors, including epilepsy syndrome, presence and type of epileptogenic lesion, and duration of post-operative follow-up. For patients who are not eligible for epilepsy surgery or for whom surgery has failed, trials of alternative AEDs or other non-pharmacological therapies, such as the ketogenic diet and neurostimulation, may improve seizure control. Ongoing research into novel antiepileptic agents, improved techniques to optimise epilepsy surgery, and other non-pharmacological therapies fuel hope to reduce the proportion of individuals with uncontrolled seizures. With the plethora of gene discoveries in the epilepsies, “precision therapies” specifically targeting the molecular underpinnings are beginning to emerge and hold great promise for future therapeutic approaches.


via The management of epilepsy in children and adults. – Abstract – Europe PMC

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[WEB SITE] You have epilepsy… so what!

By Adeela Akmal


Epilepsy is not a disease, it is a disorder. People who have epilepsy are fully capable of leading a normal life. Read on to find out more…


Epilepsy is not a disease, it is a disorder. People who have epilepsy are fully capable of leading a normal life. Read on to find out more…

Epilepsy is a neurological condition that is estimated to occur in 0.5% to 1% of the population of any country. According to the Department of Neurology, Jinnah Postgraduate Medical Centre, Karachi, one in every hundred Pakistani has epilepsy and at least 5 family members are affected in some way or the other due to it. The condition is also twice as common in rural areas as compared to the urban. Epilepsy is a sudden surge of electrical activity in the brain that causes a temporary disturbance in the messaging systems between the brain cells.

Unfortunately, the condition has been stigmatised in the country due to misinformation. Recently, a press conference was held in a bid to create awareness regarding epilepsy at Najumuddin Auditorium at Jinnah Postgraduate Medical Centre (JPMC) to squash the certain stereotypes of the disorder. According to Prof Dr Hasan Aziz, “It is a common misconception among unaware people that an epilepsy attack is a work of some ‘evil spirit’ or ‘supernatural beings’, or that person can be cured by sniffing a shoe. It is not contagious and is rarely hereditary; and it does not affect your intellectual capabilities. A person can live their life normally if they take their prescribed medicines on time, take care of their diet and sleep.”

There have been many famed personalities like Newton, Tolstoy, Socrates, Da Vinci, to our very own Abdul Sattar Edhi, Nadia Jamil and Suhaee Abro, who are epileptic.

Nadia Jamil, actress and mother of two young boys, was diagnosed with epilepsy in 2011, and has not let that get in the way of her work, “As an actress I need my body to work and as a mother I always have to be energetic. Initially, there was a sense of panic and the limitations of my body hit me, like it would for a person with asthma or diabetes. But, medications have helped me. I cook, clean, shop for groceries, ride a bicycle, work and run after my boys without fear. Epilepsy can be handled with medications and a little care in terms of lifestyle – getting proper rest and full sleep. To anyone who has epilepsy, you are not sick, there isn’t anything that you can’t accomplish. It’s not a disease, it is a condition which can be controlled if taken care,” stated Nadia Jamil while talking to this scribe.


According to National Epilepsy Centre (NEC) at JPMC, in about 70 per cent of the cases, there seems to be no obvious cause of the condition. However, for the remaining cases, strokes, brain tumours, head trauma (such as occurring during a car crash), infectious diseases (for example: AIDS), congenital abnormalities (prenatal injury, or brain damage that occurred before birth), or development disorders (such as autism or neurofibromatosis) are some of the factors that increase the risk of epilepsy.


The key symptom of epilepsy is repeated seizures. One should immediately consult a doctor if it is a recurring matter. A person may experience convulsions with no fever, short spells of blackout, fainting spells during which bowel and bladder isn’t in control. The person may do unexplainable things such as suddenly become stiff, have bouts of blinking or chewing, or do repetitive or jerking movements.


For diagnosis, a person goes through a complete physical and neurological exam, and their clinical history is taken along with a detailed account of their seizure that occurred. Additional testing may include EEG (Electroencephalogram) that detects the brain’s electrical activity.

The epileptic seizures can be controlled with antiepileptic drug (AED) therapy. The doctor will prescribe the dosage according to several factors for a particular individual like age, gender, overall health and the severity of the seizures. So, it is mandatory to take the prescribed dosage with punctuality.

In some cases, if there is an underlying brain condition that is causing these seizures, surgeries can be recommended. And, if the AEDs don’t work, the next step could be surgery.


While one is still trying to control their condition, it is imperative to take certain precautions. An epileptic person should avoid all activities that can potentially put their lives at risk like riding or driving a vehicle, working in factories (like having to operate heavy or open machinery) or heights. Anything that involves swimming, working near an open flame should be done under supervision.

There are also certain triggers that can provoke seizures in people with epilepsy like missing medications, consuming recreational drugs and alcoholic beverages, lack of sleep and other drugs that may interfere with the prescribed medicines.

What to do when someone is having a seizure?

Do not panic: If you witness someone having seizures, it’s important for you to stay calm in order to help someone.

Protect the person from potential injuries: Help keeping them from falling and gently guide them to the floor. Remove any objects or furniture that may injure the person.

Place a pillow under their head: If they are already on the ground, turn them to one side and loosen the clothing around their neck. Place something soft under their head.

Don’t force anything: Do not forcibly open or put anything in mouth (water, spoon, cloth). You may end up hurting them and yourself.

Record everything: Record the event on your device to show it to the doctor. Pay close attention to the body movement during seizure, how long it lasted, how the person reacted after and possible injuries.


via You have epilepsy… so what!

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[NEWS] Effective epilepsy medication without the side effects? | Epilepsy Research UK

Posted Mar 9 2018 in Anti-epileptic drugs


Approximately 60-70% of people with epilepsy will have their seizures controlled with medication. But even when epileptic seizures are controlled with medication the drugs used may have unpleasant, unwanted side effects. Ideally what patients and clinicians are looking for is a drug which works effectively and has no down side. Now new research from the Australian National University aims to look at the molecular level to find a way of reducing negative side effects without reducing the drug’s efficacy.  If you would like to read more about this study please click on the link here:


via Effective epilepsy medication without the side effects? | Epilepsy Research UK

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