Posts Tagged ischemic stroke
[ARTICLE] Prediction of Upper Limb Motor Recovery after Subacute Ischemic Stroke Using Diffusion Tensor Imaging: A Systematic Review and Meta-Analysis – Full Text
[Abstract] Mobile game-based virtual reality rehabilitation program for upper limb dysfunction after ischemic stroke.
[Abstract] Effect of Electroacupuncture Intervention on Rehabilitation of Upper Limb Motor Function in Patients with Ischemic Stroke. – PubMed – NCBI
To observe the effect of electro-elongated needle intervention on rehabilitation of upper limb motor function in patients with ischemic stroke.
A total of 100 ischemic stroke patients were equally and randomly divided into manual acupuncture group and electro-elongated needle group (n=50 cases/group). For patients of the manual acupuncture group, filiform needles were respectively inserted into Jianyu (LI 15), Jiquan (HT 1), Shousanli (LI 10), Neiguan (PC 6) and Hegu (LI 4) on the affected side, manipulated with lifting-thrusting reinforcing or reducing method for 40 min, once daily for two weeks except the weekends, and for those of the electro-elongated needle group, elongated needles were repeatedly penetrated from LI 15 to Binao (LI 14), and from LI 10 to Waiguan (TE 5) on the affected side, followed by electrical stimulation for 40 min, once daily for two weeks except weekends. The therapeutic effect of manual acupuncture and electro-elongated needle for upper extremity rehabilitation was assessed according to the modified upper-extremity Fugl-Meyer Assessment (FMA) and Wolf Motor Function Test (WMFT) separately. The surface electromyogram (sEMG) of the deltoid muscle was recorded by using a Megawin Surface Electrogram System and the root mean square (RMS) of the amplitude of sEMG was used to evaluate the functional state of the deltoid muscle.
After the treatment, the score of FMA and WMFT in both manual acupuncture and electro-elongated needle groups were significantly increased compared with pre-treatment in the same one group (P<0.01), suggesting an improvement of the motor function of the upper limbs, but RMS ratios of the amplitude of sEMG were evidently decreased in both groups (P<0.05, P<0.01), suggesting a relief of the abnormal muscular tension. The therapeutic effects of the electro-elongated needle were obviously superior to those of manual acupuncture in up-regulating FMA and WMFT scores and down-regulating RMS ratio (P<0.01).
Electro-elongated needle therapy can effectively improve the motor function of upper limb in ischemic stroke patients and has a better effect in comparison with simple manual acupuncture.
21 DEC 2015
Over recent decades, experimental and clinical stroke studies have identified a number of neurorestorative treatments that stimulate neural plasticity and promote functional recovery. In contrast to the acute stroke treatments thrombolysis and endovascular thrombectomy, neurorestorative treatments are still effective when initiated days after stroke onset, which makes them applicable to virtually all stroke patients. In this article, selected physical, pharmacological and cell-based neurorestorative therapies are discussed, with special emphasis on interventions that have already been transferred from the laboratory to the clinical setting. We explain molecular and structural processes that promote neural plasticity, discuss potential limitations of neurorestorative treatments, and offer a speculative viewpoint on how neurorestorative treatments will evolve.
[ARTICLE] Influence of Kinesitherapy on Gait in Patients with Ischemic Stroke in the Chronic Period – Full Text PDF
AIM: The study aims to trace the influence of specialized kinesitherapeutic methodology (SKTM) on gait in patients with ischemic stroke in the chronic period (ISChP).
MATERIAL AND METHODS: The study was conducted with 56 patients with ISChP (duration of the disease up to 1 year). For determining changes in gait before and after the treatment a cadence of gait and maximum movement speed were taken into consideration. To determine the cadence, steps are counted for covering 6 meters and 10 meters respectively. The maximum speed of the gait is determined in m / min by dividing undergone distance (m) and time (min).
RESULTS: Patients were found to significantly normalize the parameters of gait. Compared to the initial data, there is a significant reduction in the number of steps on 6 and 10 meters and a tendency to increase the speed of gait, with the significant change during the 1st month with a level of significance of p <0.001.
CONCLUSION: The applied specialized kinesitherapeutic methodology continued later as exercise program at home, which significantly improved gait cadence and speed of movement in patients with ischemic stroke in the chronic period and is with a supportive prolonged exposure.
[ARTICLE] Non-invasive electric current stimulation for restoration of vision after unilateral occipital stroke
Occipital stroke often leads to visual field loss, for which no effective treatment exists. Little is known about the potential of non-invasive electric current stimulation to ameliorate visual functions in patients suffering from unilateral occipital stroke. One reason is the traditional thinking that visual field loss after brain lesions is permanent. Since evidence is available documenting vision restoration by means of vision training or non-invasive electric current stimulation future studies should also consider investigating recovery processes after visual cortical strokes. Here, protocols of repetitive transorbital alternating current stimulation (rtACS) and transcranial direct current stimulation (tDCS) are presented and the European consortium for restoration of vision (REVIS) is introduced. Within the consortium different stimulation approaches will be applied to patients with unilateral occipital strokes resulting in homonymous hemianopic visual field defects. One goal is to evaluate effects of the stimulation on vision parameters, vision-related quality of life, and physiological parameters that allow conclude about the mechanisms of vision restoration as induced by electrical current stimulation. These include EEG-spectra and coherence measures, and visual evoked potentials. The design of stimulation protocols involves an appropriate sham-stimulation condition and sufficient follow-up periods to test whether the effects are stable.
This is the first application of non-invasive current stimulation for vision rehabilitation in stroke-related visual field deficits. Positive results of the trials could have far-reaching implications for clinical practice. The ability of non-invasive electrical current brain stimulation to modulate the activity of neuronal networks may have implications for stroke rehabilitation also in the visual domain.
Researchers at Weill Cornell Medical College have developed a new mathematical method that can predict the type and severity of impairment that a patient with brain damage will have given the location of their lesion.
With further development, this tool could not only allow clinicians to make more precise prognoses, but could also help them provide individual patients with personalized treatment plans, investigators say.
This so-called “glassbrain” visualizes the brain’s structural connectivity network and the effects on the network of a particular ischemic stroke lesion, plotted in green. Each sphere represents a different gray matter region, with blue indicating that the stroke had no effect on the gray matter region’s connectivity to the rest of the brain and red indicating that the stroke had some effect on the gray matter region’s connectivity to the rest of the brain. Pipes between the spheres indicate that a structural connection exists between the gray matter regions, with connections not affected by stroke drawn in black and those effected by the stroke in red. Image credit: Dr. Amy Kuceyski
Dr. Amy Kuceyeski, an assistant professor of mathematics in the Department of Radiology and at the Feil Family Brain and Mind Research Institute at Weill Cornell, pioneered this computational Network Modification (NeMo) Tool, which calculates how much damage a patient has sustained to their brain’s white matter, the tissue that connects different brain regions. When using this tool to evaluate patients with either multiple sclerosis (MS) or stroke, Dr. Kuceyeski and her team, who imported data into the NeMo tool that was derived solely from earlier MRI images of the brain, found that white matter damage can be used to predict physical and cognitive impairments a patient will experience. This research, which was published in two separate journals in November 2014 and February of this year, shows that using the NeMo tool could provide clinicians with an easy way to deliver more accurate prognoses and rehabilitation plans for their patients.